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228-230 Optimizing Cardiac Fatty Acid and © 2006 Sage Publications 10.1177/1089253206291150 http://scv.sagepub.com Glucose Metabolism as an Approach hosted at http://online.sagepub.com to Treating Heart ...
cardiac metabolism . Although underappreciated as a potential therapeutic target, the optimal metabolic milieu of a failing heart is still largely unknown and subject to debate. Because glucose naturally has ...
the efficiency of oxygen utilization by the tissue. Inhibiting fatty acid oxidation and stimulating glucose oxidation can significantly improve cardiac efficiency ( cardiac work/oxygen consumed). This metabolic ...
serve as an additional approach for managing HF, but further studies are warranted. Myocardial Fatty Acid Metabolism and Cardiac Performance in Heart Failure Helena Tuunanen, MD, PhD, Heikki Ukkonen, MD ...
This review article discusses pharmacological approaches to optimizing myocardial metabolism during ischemia. Fatty acids are the main fuel for the healthy heart, with a lesser contribution coming ...
metabolism to switch the energy substrate towards glucose optimizing O2 consumption at the expense of energy efficiency. An indirect correlation was found between fatty acid translocase (FAT/CD36) and GLUT4 ...
and myocardial infarction, the complication of myocardial ischemia remains a major cause of mortality and morbidity worldwide. A novel approach that entails improving and optimizing cardiac energy metabolism ...
, ischaemic heart disease still remains a major health problem. Therefore, the development of new treatment strategies is still required. One exciting new approach is to optimize cardiac energy metabolism ...
Media, LLC 2009 Abstract Introduction Purpose Mildronate and orotic acid act as modulators of energy metabolism and are considered as cardioprotective The optimization of myocardial energy metabolism has ...
strategies to protect the high-risk aged heart.2 The impairment of substrate flexibility (balance between glucose usage and fatty acid oxidation) contributes to cardiac injury during IR as well as heart ...
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