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www.arnoldpublishers.com/journals PAPER In vitro - activated human lupus T cells express normal estrogen receptor proteins which bind to the estrogen response element 1 2 1 1 R Suenaga *, V Rider , MJ Evans and NI Abdou 1 2 ...
activity . apoptosis, estrogen , lupus , T cells , testosterone Introduction Defective control of T cell apoptosis is considered to be one of the pathogenetic mechanisms in systemic lupus erythematosus (SLE ...
neutrophil serine proteases and myeloperoxidase expression , promoted the production of nitric oxide and monocyte chemoattractant protein-1, and altered adaptive immune T cell subsets. However, activation ...
of testosterone upon this parameter. This suggestion is corroborated by various studies. In vitro it has been shown that estrogen induces polyclonal activation of B cells in humans : it increased IgG and IgM ...
-type ER expression vectors respectively. The transfected cells were incubated for 24 h in the presence (+) or absence (−) of 10 −7 M E 2 and CAT activities were normalized relative to β-galactosidase ...
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production by B1 cells in vitro was also enhanced in the presence of endocrine disruptors including DES and BPA. Estrogen receptor (ER) expression was upregulated in B1 cells in aged BWF1 mice that developed ...
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V , Abdou NI 1998 Peripheral blood T cells and monocytes and B cell lines derived from patients with lupus express estrogen receptor transcripts similar to those of normal cells . J Rheumatol 25 ...
suppressive activity during the night and that expression of this activity requires normal sleep. So far, fixed numbers of nTreg and reporter T cells were incubated. However, these experiments did not consider ...
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