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interventions. At present there is no known imaging marker for remyelination . While positron emission tomography (PET) has ample sensitivity and specificity, an appropriate tracer is lacking and spatial ...
Remyelination is crucial to recover from inflammatory demyelination in multiple sclerosis (MS). Investigating remyelination in vivo using magnetic resonance imaging (MRI) is difficult in MS, where ...
was also captured within the retina. Finally, fine visual function was renewed after the remyelination program was completed. In conclusion, our in vivo imaging results showed that new olig2+ cells were born ...
In vivo imaging of white matter is important for the mechanistic understanding of demyelination and evaluation of remyelination therapies. Although white matter can be visualized by a strong coherent ...
remyelination , as measured for MS. by magnetic resonance diffusion First the authors showed that, tensor imaging , histological staining after EAE induction, disease progres- and electron microscopy. sion ...
Objective:To investigate the clinical relevance of individual profiles of cortical and white matter lesion myelin content changes combining magnetisation transfer imaging (MTI) and 11C-PiB-positron ...
remyelination activity will be required, and very recently a new imaging modality named q‐space myelin map imaging has been developed. Together with various candidate remyelination medicines under clinical ...
< 0.0001; r = 0.33; P = 0.069, respectively), an imaging marker of neurodegeneration. Interestingly, we also showed an association between the periventricular failure of remyelination and regional cortical ...
SignificancePutative imaging biomarkers for myelin in MS have been correlated with pathological evidence of myelin loss in the context of a complex pathological environment. However, they have ...
Magnetic resonance imaging (MRI) of focal or diffuse myelin damage or remyelination may provide important insights into disease progression and potential treatment efficacy in multiple sclerosis ...
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