Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
demyelination. Our data support the hypothesis that even in a non -primary immune model of demyelination, manipulating the immune system can be beneficial in myelin repair. Enhancement central nervous in immune ...
is to enhance neuroprotective autoimmunity inside the brain, believed to be mediated, at least in part, by the release of neurotrophic factors within the nervous system from infiltrating immune cells ...
surveillance in the injured central nervous system . Introduction Peripheral nerve injury initiates a large number of morphological and molecular changes in the damaged nervous system that are particularly ...
environment for better neuronal regeneration and functional recovery after adult mammalian central nervous system (CNS) injury. However, activated immune cells can also induce secondary damage of intact tissue ...
recruitment and maturation of oligodendrocyte lineage cells to enhance remyelination . multiple sclerosis, remyelination , extracellular matrix, CSPGs Introduction Multiple sclerosis is an inflammatory condition ...
(EAE) is one of the well-established rodent models of MS, in which demyelination in the central nervous system (CNS) is induced by the treatment with antibodies against myelin binding protein (MBP ...
system lesions. Conversely, recombinant IL4I1 administration into central nervous system lesions reduces proinflammatory macrophage density, enhances remyelination , and rescues remyelination impairment ...
immune system can modify subsequent disease activity. The spectre of SARS-CoV-2 has challenged this general approach, however, necessitating a reappraisal of the risks and benefits of non -specific ...
:0046330), axonogenesis (GO:0007409), protein tyrosine kinase activity (GO:0004713), central nervous system development (GO:0007417), positive regulation of immune system process (GO:0002684) and regulation ...
as mean ± SEM; n = 5). High dose vitamin D promotes severe, persistent disability in EAE Vitamin D exerts immunomodulatory effects on cells within the innate and adaptive immune system , which widely express ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!