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During the next few years investigations may provide many final solutions to the immunologic complications of hematopoietic and immunocompetent tissue grafting . REVIEW CLINICAL the next few During ...
. The main criterion for donor selection is HLA compatibility. In this review we discuss the current clinical evidence of HLA matching in unrelated HSCT. In this context, we address methodical aspects ...
This review article deals with the transfer of human lymphoid or hematopoietic tissues to severely immunodeficient mice to create new small animal models for the study of human biology and disease ...
Induction of tolerance is likely to be necessary for the achievement of successful xenotransplantation, because immune responses against xenogeneic tissues or organs are vigorous. Currently ...
& 2008 Nature Publishing Group All rights reserved 0887-6924/08 $30.00 www.nature.com/leu SPOTLIGHT REVIEW Chemokine-mobilized adult stem cells; defining a better hematopoietic graft LM Pelus and S Fukuda ...
Mesenchymal stromal cells (MSCs) can be isolated from several human tissues and expanded for clinical use. MSCs are identified by phenotypic and functional characteristics, and are poor Ag-presenting ...
in nonspecific tissue injury that can cause short- and long-term adverse effects as well as incite and amplify graft -versus-host-disease (GVHD). The delivery of targeted radiotherapy to hematopoietic tissues ...
current concepts to stimulate reconstitution of a peripheral and polyclonal T-cell compartment following allogeneic transplantation such as graft manipulation (i.e., T-cell depletion), transfusion of ex ...
is of particular interest to the field of transplantation, beyond any roles in limiting or promoting allograft rejection or graft -versus host disease. Within this review , we discuss the current understanding of ILCs ...
that the generation of humanized organoids can open up new vistas for the translation of research findings in preclinical animal models of tumor immunology . Convergence of Tissue Engineering and Cancer Research Current ...
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