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Clin-Alert

Clin-Alert Volume 40, Number 2 January 31, 2002 BACILLUS CALMETTE-GURIN (Intravesical) Prostate Abscess (First Report*) No. 14 A 47-year-old male patient developed perineal pain approximately three years after starting intravesical therapy with bacillus Calmette-Gurin for bladder carcinoma. A physical examination was normal with the exception of a slight induration on the right side if the prostate. Treatment with levofloxacin for suspected prostatitis was un- successful in reversing symptoms, and the patient required further eval- uation. Upon re-examination a left perineal mass was detected. Com- puted tomography of the area revealed a hypoattenuating mass consistent with a prostate abscess. Treatment included surgical drain- age. Examination and culture of the drainage fluid revealed an acid fast bacilli infection (Mycobacterium bovis), which was treated with isoniazid and ethambutol. Continued treatment with this regimen was in progress at the time of publication. The authors noted that this is the first case report of prostate abscess after bacillus Calmette-Gurin therapy for bladder cancer. They sug- gested that prompt initiation of antituberculin therapy is essential in opti- mizing beneficial patient outcomes. Bacillus Calmette-Gurin ["TICE," "TheraCys"] Matlaga BR et al (Dept Urology, Wake Forest Univ, Sch Med, Winston-Salem, NC) Prostate abscess following intravesical bacil- lus Calmette-Gurin http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clin-Alert SAGE

Clin-Alert

Abstract

Volume 40, Number 2 January 31, 2002 BACILLUS CALMETTE-GURIN (Intravesical) Prostate Abscess (First Report*) No. 14 A 47-year-old male patient developed perineal pain approximately three years after starting intravesical therapy with bacillus Calmette-Gurin for bladder carcinoma. A physical examination was normal with the exception of a slight induration on the right side if the prostate. Treatment with levofloxacin for suspected prostatitis was un- successful in reversing symptoms, and the patient required further eval- uation. Upon re-examination a left perineal mass was detected. Com- puted tomography of the area revealed a hypoattenuating mass consistent with a prostate abscess. Treatment included surgical drain- age. Examination and culture of the drainage fluid revealed an acid fast bacilli infection (Mycobacterium bovis), which was treated with isoniazid and ethambutol. Continued treatment with this regimen was in progress at the time of publication. The authors noted that this is the first case report of prostate abscess after bacillus Calmette-Gurin therapy for bladder cancer. They sug- gested that prompt initiation of antituberculin therapy is essential in opti- mizing beneficial patient outcomes. Bacillus Calmette-Gurin ["TICE," "TheraCys"] Matlaga BR et al (Dept Urology, Wake Forest Univ, Sch Med, Winston-Salem, NC) Prostate abscess following intravesical bacil- lus Calmette-Gurin
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