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A 43-year-old man with recurrent pulmonary emboli associated with antithrombin III deficiency is presented. After laparotomy for penetrating abdominal trauma, thrombophlebitis and emboli were treated ...
Two teenage brothers with recurrent thromboembolic disease were found to have antithrombin III deficiency. A family study spanning four generations revealed a total of 10 members with antithrombin ...
A 57-year-old man with antithrombin III deficiency with deep vein thrombosis and pulmonary thromboembolism after surgery for colon cancer was managed with warfarin and inferior vena cava filtration ...
Background:Thrombophilia is a coagulation disorder closely associated with venous thromboembolism . Hereditary antithrombin III (AT III ) deficiency is a type of genetic thrombophilia. In China ...
antithrombin binding moiety of heparin. Through the activation of antithrombin it inhibits Factor Xa, the activation of thrombin, and the subsequent coagulation cascade. Fondaparinux is approved ...
thromboembolism , Xa factor inhibitor, Case report Learning points Patients with low antithrombin III (AT III ) levels may be heparin-resistant and are at an increased risk for arteriovenous thromboembolic disease ...
is a predisposition to thrombosis. Genetic causes include antithrombin III , protein C, protein S, factor V Leiden, prothrombin 20210A allele, and MTHFR mutations. Other genetic factors causing thrombosis and pulmonary ...
of recurrent VTE or bleeding during treatment with oral ximelagatran (24 mg twice daily) or placebo for 18 months [THRombin Inhibitor in Venous thromboEmbolism (THRIVE) III trial]. Of the 1223 patients ...
, especially E113X, in AT3 may be related to recurrent thrombosis in the pregnancy. Am. J. Med. Genet. 91:348–350, 2000. © 2000 Wiley‐Liss, Inc. INTRODUCTION Antithrombin (AT) III , a single chain glycoprotein ...
, detected in six patients from two Serbian families (Fig. A) with recurrent thrombosis at a young age. In the proposita from family 1 (A‐ III ‐1; Fig. A), the venous thromboembolism occurred ...
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