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/lp/rockefeller-university-press/fixation-of-neural-tissues-for-electron-microscopy-by-perfusion-with-4Wury0CgTA
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- Publisher
- Rockefeller University Press
- Copyright
- © 1962 Rockefeller University Press
- ISSN
- 0021-9525
- eISSN
- 1540-8140
- DOI
- 10.1083/jcb.12.2.385
- Publisher site
- See Article on Publisher Site
Abstract
This paper describes in detail a method for obtaining nearly uniform fixation of the nervous system by vascular perfusion with solutions of osmium tetroxide. Criteria are given for evaluating the degree of success achieved in the preservation of all the cellular components of the nervous system. The method permits analysis of the structural relations between cells at the electron microscopic level to an extent that has not been possible heretofore. Footnotes Submitted: 15 August 1961
Journal
The Journal of Cell Biology – Rockefeller University Press
Published: Feb 1, 1962