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EXPERIMENTAL EPIDEMIOLOGY OF TUBERCULOSIS

EXPERIMENTAL EPIDEMIOLOGY OF TUBERCULOSIS 1. After intraperitoneal inoculation of guinea pigs with tubercle bacilli, the microorganisms may appear in the feces and elimination may persist during 1 week. Subsequently during several weeks no tubercle bacilli can be recovered from the feces. 2. When tuberculosis is widely disseminated in the body of guinea pigs, tubercle bacilli are discharged with the feces. 3. Tubercle bacilli are occasionally eliminated in the bile of guinea pigs immediately after inoculation but are almost constantly found in the bile after several weeks when the disease is well established. 4. Tubercle bacilli are eliminated in the urine of experimentally infected guinea pigs only when infection is far advanced. Footnotes Submitted: 7 February 1927 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Experimental Medicine Rockefeller University Press

EXPERIMENTAL EPIDEMIOLOGY OF TUBERCULOSIS

The Journal of Experimental Medicine , Volume 45 (6): 1025 – Jun 1, 1927

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Publisher
Rockefeller University Press
Copyright
© 1927 Rockefeller University Press
ISSN
0022-1007
eISSN
1540-9538
DOI
10.1084/jem.45.6.1025
Publisher site
See Article on Publisher Site

Abstract

1. After intraperitoneal inoculation of guinea pigs with tubercle bacilli, the microorganisms may appear in the feces and elimination may persist during 1 week. Subsequently during several weeks no tubercle bacilli can be recovered from the feces. 2. When tuberculosis is widely disseminated in the body of guinea pigs, tubercle bacilli are discharged with the feces. 3. Tubercle bacilli are occasionally eliminated in the bile of guinea pigs immediately after inoculation but are almost constantly found in the bile after several weeks when the disease is well established. 4. Tubercle bacilli are eliminated in the urine of experimentally infected guinea pigs only when infection is far advanced. Footnotes Submitted: 7 February 1927

Journal

The Journal of Experimental MedicineRockefeller University Press

Published: Jun 1, 1927

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