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M. Bessis, J. Breton-Gorius (1959)
Differents aspects du fer dans l'organismeThe Journal of Biophysical and Biochemical Cytology, 6
E. Dempsey, G. Wislocki (1955)
THE USE OF SILVER NITRATE AS A VITAL STAIN, AND ITS DISTRIBUTION IN SEVERAL MAMMALIAN TISSUES AS STUDIED WITH THE ELECTRON MICROSCOPEThe Journal of Biophysical and Biochemical Cytology, 1
First appearance of dense intramitochondrial deposits (silica) in a portion of mitochondria (arrows). FIGURE O Detail of deposits in two modified mitochondria. The mitochondrion on the left is swollen, with thinned contents and modified cristae. The mitoehondrion on the right remains dense but the cristae have almost disappeared. W E B R I E F N O T E S T h e fate of the siliceous bodies is easily followed. By progressive swelling, the mitochondria break up, the siliceous bodies being freed in the degenerating cytoplasm. W i t h the latter they proceed to the l u m i n a of the u r i n a r y tubule into the casts, with which they are finally eliminated. After 2 days, w h e n the siliceous bodies begin to a p p e a r in the necrotic substance of the casts, the silica content of the whole kidney becomes nearly normal. Recently, the electron microscope has provided us with a means of detecting i n t r a m i t o c h o n d r i a l deposits following silver (Dempsey, 1955) or iron (ferritin, Bessis, 1959) treatment.
The Journal of Cell Biology – Rockefeller University Press
Published: Jan 1, 1961
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