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CHANGES IN THE TITER OF ANTIPNEUMOCOCCAL HUMORAL IMMUNITY IN ADULT HUMAN BEINGS

CHANGES IN THE TITER OF ANTIPNEUMOCOCCAL HUMORAL IMMUNITY IN ADULT HUMAN BEINGS Fifty-five individuals were tested to determine the pneumococcidal promoting activity of their serum against Types I and II pneumococci. By repeated tests an attempt was made to study the constancy of the degree of their immunity over intervals of 2 to 6 months. In this group were included nine persons with common colds and twelve cases of a severe influenza-like infection. Fifteen of the fifty-five cases showed a change in titer of their humoral immunity against either Type I or Type II or both. Three of these showed an increase, and twelve a decrease. This reaction in most instances was a specific one in that the altered reaction toward one type was not associated with a similar change toward the other type pneumococcus. Colds and influenza-like infections apparently exerted no effect upon the titer of humoral immune substances. Footnotes Submitted: 8 June 1933 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Experimental Medicine Rockefeller University Press

CHANGES IN THE TITER OF ANTIPNEUMOCOCCAL HUMORAL IMMUNITY IN ADULT HUMAN BEINGS

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References (8)

Publisher
Rockefeller University Press
Copyright
© 1933 Rockefeller University Press
ISSN
0022-1007
eISSN
1540-9538
DOI
10.1084/jem.58.2.245
Publisher site
See Article on Publisher Site

Abstract

Fifty-five individuals were tested to determine the pneumococcidal promoting activity of their serum against Types I and II pneumococci. By repeated tests an attempt was made to study the constancy of the degree of their immunity over intervals of 2 to 6 months. In this group were included nine persons with common colds and twelve cases of a severe influenza-like infection. Fifteen of the fifty-five cases showed a change in titer of their humoral immunity against either Type I or Type II or both. Three of these showed an increase, and twelve a decrease. This reaction in most instances was a specific one in that the altered reaction toward one type was not associated with a similar change toward the other type pneumococcus. Colds and influenza-like infections apparently exerted no effect upon the titer of humoral immune substances. Footnotes Submitted: 8 June 1933

Journal

The Journal of Experimental MedicineRockefeller University Press

Published: Aug 1, 1933

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