Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Accelerating effect of 2,4,6-trinitrophenol on the glycolytic rate of human red cells.

Accelerating effect of 2,4,6-trinitrophenol on the glycolytic rate of human red cells. ABSTRACT A n u m b e r o f instantaneous changes occurred when picrate was a d d e d to a suspension o f human red cells in stead)' state with respect to glycolysis and ion distribution across the m e m b r a n e at p H 7.40. T h e rate o f glycolysis increased, without change in glycolytic quotient, to a new steady-state value, the effect reaching a m a x i m u m o f 1.75 times the rate o f the control at 0.5 mM picrate. Inorganic phosphate (Pi) was released at a relatively constant rate, increasing with picrate concentration to 1.0 mmol Pl/liter cells x h at 5-6 mM picrate. T h e steadystate concentration o f A T P and 1,3-diphosphoglycerate (1,3-DPG) decreased to new stable values within 15-45 rain after the addition o f picrate. T h e A T P level was affected only at picrate concentrations o f I mM or more, and the level o f A T P stabilized at 75% of the control values at 4 mM o f picrate. In contrast, 1,3-DPG concentrations decreased to 40% o f the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of General Physiology Rockefeller University Press

Accelerating effect of 2,4,6-trinitrophenol on the glycolytic rate of human red cells.

The Journal of General Physiology , Volume 70 (5): 661 – Nov 1, 1977

Loading next page...
 
/lp/rockefeller-university-press/accelerating-effect-of-2-4-6-trinitrophenol-on-the-glycolytic-rate-of-85lFtlDkjo

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Rockefeller University Press
Copyright
Copyright © 1977 by The Rockefeller University Press
ISSN
0022-1295
eISSN
1540-7748
DOI
10.1085/jgp.70.5.661
Publisher site
See Article on Publisher Site

Abstract

ABSTRACT A n u m b e r o f instantaneous changes occurred when picrate was a d d e d to a suspension o f human red cells in stead)' state with respect to glycolysis and ion distribution across the m e m b r a n e at p H 7.40. T h e rate o f glycolysis increased, without change in glycolytic quotient, to a new steady-state value, the effect reaching a m a x i m u m o f 1.75 times the rate o f the control at 0.5 mM picrate. Inorganic phosphate (Pi) was released at a relatively constant rate, increasing with picrate concentration to 1.0 mmol Pl/liter cells x h at 5-6 mM picrate. T h e steadystate concentration o f A T P and 1,3-diphosphoglycerate (1,3-DPG) decreased to new stable values within 15-45 rain after the addition o f picrate. T h e A T P level was affected only at picrate concentrations o f I mM or more, and the level o f A T P stabilized at 75% of the control values at 4 mM o f picrate. In contrast, 1,3-DPG concentrations decreased to 40% o f the

Journal

The Journal of General PhysiologyRockefeller University Press

Published: Nov 1, 1977

There are no references for this article.