Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Werner's Syndrome

Werner's Syndrome Werner's Syndrome A Case Repor 1 Maurice M. Pomeranz , M.D. New York, N. Y. Excerpt THE PAST generation has witnessed a revolutionary change in our conception of bone function. Considered originally an inert framework for the anchorage or support of viscera, or a part of the blood-forming system, the skeleton is now known to be a functioning organ of vital importance in the metabolism of the body. As our understanding of the role of the osseous system unfolded, the education and training of the roentgenologist broadened so that he became familiar with the general diseases which are reflected in bones. Few phases of the field of clinical medicine have been left unexplored by the progressive roentgenologist. Imperceptibly his role has changed and he has become as thoroughly versed in medical, as his predecessor was in surgical, radiography. Clear evidence of the changing status of the roentgenologist is his familiarity with the radiographic appearances of the deficiency states and of the constitutional disorders which leave their imprint on the osseous system. Especially in the field of orthopedics he must be thoroughly familiar with the bodily conditions which are accompanied by skeletal changes, since patients with orthopedic complaints suffer some constitutional diseases in which the orthopedic manifestations are inconsequential. Illustrative of the foregoing is the rare condition to be reported here—Werner's syndrome—which was recently studied at the Hospital for Joint Diseases and which was correctly identified from the roentgenograms. Case Report L. K., a white, unmarried female, aged 35, visited the clinic on June 5, 1947, complaining of a chronic ulcer of the right foot. After preliminary examination, she was admitted to the hospital for lumbar sympathetic block in the expectation of healing the ulcer. The patient's mother died at 50 years of diabetes and a heart condition. The father was alive and well but also suffering from diabetes. Two brothers were alive and well. The patient had poliomyelitis when nine months old, followed by weakness of hips, for which she was placed in a cast. At the age of three, she was able to walk again but was left with an everted right foot which was corrected at the age of eleven at a local hospital. She was able to wear ordinary shoes until 18 years of age but callosities developed which compelled her to purchase special shoes. At the age of 23, the patient lost her mother. She felt her loss keenly and in the succeeding three months she lost 25 pounds, which she had never regained, so that her weight on admission was 77 pounds. At the age of 24, she experienced difficulty in vision and the diagnosis of “cataract” was made. Bilateral cataract extraction was performed four years later. No further ocular disturbances occurred until the age of 34 years, when she injured her right eye, which had since been subject to recurring inflammation, for which treatment was still being received. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Radiology Radiological Society of North America, Inc.

Werner's Syndrome

Pomeranz, Maurice M.
Radiology , Volume 51 (4): 521 – Oct 1, 1948
Download PDF
4 pages

Loading next page...
 
/lp/radiological-society-of-north-america-inc/werner-s-syndrome-l8ao21FG5v

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Radiological Society of North America, Inc.
Copyright
Copyright © 1948 by Radiological Society of North America
ISSN
1527-1315
eISSN
0033-8419
DOI
10.1148/51.4.521
pmid
18893285
Publisher site
See Article on Publisher Site

Abstract

Werner's Syndrome A Case Repor 1 Maurice M. Pomeranz , M.D. New York, N. Y. Excerpt THE PAST generation has witnessed a revolutionary change in our conception of bone function. Considered originally an inert framework for the anchorage or support of viscera, or a part of the blood-forming system, the skeleton is now known to be a functioning organ of vital importance in the metabolism of the body. As our understanding of the role of the osseous system unfolded, the education and training of the roentgenologist broadened so that he became familiar with the general diseases which are reflected in bones. Few phases of the field of clinical medicine have been left unexplored by the progressive roentgenologist. Imperceptibly his role has changed and he has become as thoroughly versed in medical, as his predecessor was in surgical, radiography. Clear evidence of the changing status of the roentgenologist is his familiarity with the radiographic appearances of the deficiency states and of the constitutional disorders which leave their imprint on the osseous system. Especially in the field of orthopedics he must be thoroughly familiar with the bodily conditions which are accompanied by skeletal changes, since patients with orthopedic complaints suffer some constitutional diseases in which the orthopedic manifestations are inconsequential. Illustrative of the foregoing is the rare condition to be reported here—Werner's syndrome—which was recently studied at the Hospital for Joint Diseases and which was correctly identified from the roentgenograms. Case Report L. K., a white, unmarried female, aged 35, visited the clinic on June 5, 1947, complaining of a chronic ulcer of the right foot. After preliminary examination, she was admitted to the hospital for lumbar sympathetic block in the expectation of healing the ulcer. The patient's mother died at 50 years of diabetes and a heart condition. The father was alive and well but also suffering from diabetes. Two brothers were alive and well. The patient had poliomyelitis when nine months old, followed by weakness of hips, for which she was placed in a cast. At the age of three, she was able to walk again but was left with an everted right foot which was corrected at the age of eleven at a local hospital. She was able to wear ordinary shoes until 18 years of age but callosities developed which compelled her to purchase special shoes. At the age of 23, the patient lost her mother. She felt her loss keenly and in the succeeding three months she lost 25 pounds, which she had never regained, so that her weight on admission was 77 pounds. At the age of 24, she experienced difficulty in vision and the diagnosis of “cataract” was made. Bilateral cataract extraction was performed four years later. No further ocular disturbances occurred until the age of 34 years, when she injured her right eye, which had since been subject to recurring inflammation, for which treatment was still being received.

Journal

Radiology – Radiological Society of North America, Inc.

Published: Oct 1, 1948

There are no references for this article.