Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

A Case of Sarcosporidial Infection in a Woman

A Case of Sarcosporidial Infection in a Woman A Case of Sarcosporidial Infection in a Woman 1 Col. Basil N. Kremmydas , MC , Antony M. Papadakis , M.D , Angelos Theodosiu , M.D. and G. Antonopoulos , M.D. 30 Sifnos Str., Athens 817 , Greece Excerpt The purpose of this paper is to report a case of sarcosporidial infection in man, one believed to be the nineteenth such case in the world literature and the second diagnosed in life. Sarcosporidiosis is a rather common parasitic infestation of the muscle fibers in lower vertebrates. While the heavy infestation of domestic animals has been accepted, it may be that its apparent infrequency in man results from the lack of a search for the disease. The first case—in mice—was described by Miescher in 1843, and Kartulis in 1893 reported the first human instance. The 18 undoubted cases found in the authors' review of the international literature may be recorded chronologically as follows: Kartulis (1893), Baraban and St. Remy (1894), Vuillemin (2 cases, 1902), Lorenz (1904), Darling (1909–1912), Manifold (1924), Lambert (1927), Vasudevan (1927), Feng (1932), Hewitt (1933), Hertig (1934), 2 Gilmore, Kean, and Posey (1942), Kean and Grocott (1945), Arai (2 cases, 1949), Pugh (1950), Mackinnon and Abbot (1955), McGill and Goodbody (1957). The authors' case, therefore, is the nineteenth reported, and only McGill and Goodbody have previously diagnosed the disease during life, the other cases being incidental autopsy findings. In addition, in our patient an unusual, transient, recurrent subcutaneous granulomatous condition of the extremities was present. We believe that this has not been previously described, except in the case of Pugh. The causative organism of the disease, the Sarcocystis of man, was discovered by Lindemann in 1868 and given the name Sarcocystis lindemanni in his honor by Rivolta. The life cycle of the parasite is not completely known, all our information coming from the observation of and experiments on animals. The infestation seems to take place by mouth, and the disease is conveyed via uncooked food contaminated by animal feces. The ingested spores gain entry to the endothelium of the bowel, whence they enter the blood stream and are transferred to the striated muscles where they settle within the individual muscle fibers to form cysts. Each cystic formation has a delicate hyaline wall and is characteristically divided by septa into chambers containing a large number of sickle-shaped spores. Rarely, the parasite infects the connective tissue. With rare exceptions, the infestation is asymptomatic, and, although deaths have been reported in animals, none have been demonstrated in man. There is no specific irritation of short duration, with spontaneous subsi therapy. Case Report The patient, a 52-year-old housewife and country woman, was a native of Thessaly. More than thirty years prior to our examination, she had observed an unusual granulomatous condition of the left arm. She also mentioned periodical exacerbation of local irritation of short duration, with spontaneous subsidence. Physical examination showed, on the lateral surface of the left arm, a large somewhat reddish area. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Radiology Radiological Society of North America, Inc.

A Case of Sarcosporidial Infection in a Woman

Download PDF
4 pages

Loading next page...
 
/lp/radiological-society-of-north-america-inc/a-case-of-sarcosporidial-infection-in-a-woman-YkD9RIlV8b

References (17)

Publisher
Radiological Society of North America, Inc.
Copyright
Copyright © 1964 by Radiological Society of North America
ISSN
1527-1315
eISSN
0033-8419
DOI
10.1148/83.6.1064
pmid
14226807
Publisher site
See Article on Publisher Site

Abstract

A Case of Sarcosporidial Infection in a Woman 1 Col. Basil N. Kremmydas , MC , Antony M. Papadakis , M.D , Angelos Theodosiu , M.D. and G. Antonopoulos , M.D. 30 Sifnos Str., Athens 817 , Greece Excerpt The purpose of this paper is to report a case of sarcosporidial infection in man, one believed to be the nineteenth such case in the world literature and the second diagnosed in life. Sarcosporidiosis is a rather common parasitic infestation of the muscle fibers in lower vertebrates. While the heavy infestation of domestic animals has been accepted, it may be that its apparent infrequency in man results from the lack of a search for the disease. The first case—in mice—was described by Miescher in 1843, and Kartulis in 1893 reported the first human instance. The 18 undoubted cases found in the authors' review of the international literature may be recorded chronologically as follows: Kartulis (1893), Baraban and St. Remy (1894), Vuillemin (2 cases, 1902), Lorenz (1904), Darling (1909–1912), Manifold (1924), Lambert (1927), Vasudevan (1927), Feng (1932), Hewitt (1933), Hertig (1934), 2 Gilmore, Kean, and Posey (1942), Kean and Grocott (1945), Arai (2 cases, 1949), Pugh (1950), Mackinnon and Abbot (1955), McGill and Goodbody (1957). The authors' case, therefore, is the nineteenth reported, and only McGill and Goodbody have previously diagnosed the disease during life, the other cases being incidental autopsy findings. In addition, in our patient an unusual, transient, recurrent subcutaneous granulomatous condition of the extremities was present. We believe that this has not been previously described, except in the case of Pugh. The causative organism of the disease, the Sarcocystis of man, was discovered by Lindemann in 1868 and given the name Sarcocystis lindemanni in his honor by Rivolta. The life cycle of the parasite is not completely known, all our information coming from the observation of and experiments on animals. The infestation seems to take place by mouth, and the disease is conveyed via uncooked food contaminated by animal feces. The ingested spores gain entry to the endothelium of the bowel, whence they enter the blood stream and are transferred to the striated muscles where they settle within the individual muscle fibers to form cysts. Each cystic formation has a delicate hyaline wall and is characteristically divided by septa into chambers containing a large number of sickle-shaped spores. Rarely, the parasite infects the connective tissue. With rare exceptions, the infestation is asymptomatic, and, although deaths have been reported in animals, none have been demonstrated in man. There is no specific irritation of short duration, with spontaneous subsi therapy. Case Report The patient, a 52-year-old housewife and country woman, was a native of Thessaly. More than thirty years prior to our examination, she had observed an unusual granulomatous condition of the left arm. She also mentioned periodical exacerbation of local irritation of short duration, with spontaneous subsidence. Physical examination showed, on the lateral surface of the left arm, a large somewhat reddish area.

Journal

Radiology – Radiological Society of North America, Inc.

Published: Dec 1, 1964

There are no references for this article.