Reply
Abstract
Reply Martine Cohen‐Solal and Marie‐Christine de Vernejoul INSERM U349 Hopital Lariboisiere Paris France Email: martine.cohen‐solal@inserm.lrb.ap‐hop‐paris.fr Sir, We read with interest the reply by De Broe and D'Haese concerning our article on accumulation of fluoride and strontium in dialysis patients. We fully agree with the first conclusion that we provided evidence that strontium may accumulate in patients dialyzed in developed countries. However, De Broe and his colleague have a different interpretation of our results. We agree that the role of each element in the development of osteomalacia cannot be provided by such a study. Bone strontium content is significantly higher in patients with osteomalacia, but fluoride content is significantly higher as well. The originality of the present study is to provide evidence that these two metals may have accumulated together, suggesting that both and perhaps some unmeasured other metals may contribute to the development of osteomalacia. Indeed, high levels of strontium or … Full Text of this Article