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- Publisher
- Oxford University Press
- Copyright
- Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2011. For permissions please email: journals.permissions@oup.com
- Subject
- REVIEWS
- ISSN
- 0195-668X
- eISSN
- 1522-9645
- DOI
- 10.1093/eurheartj/ehr003
- pmid
- 21444366
- Publisher site
- See Article on Publisher Site
Abstract
Chronic kidney disease (CKD) is frequently observed in patients with arterial hypertension. The same factors that promote the appearance and progression of atherosclerosis can also promote the development of CKD. Two parameters are usually measured to estimate alterations in renal function, the presence of albuminuria, and the estimation of glomerular filtration rate (GFR). Microalbuminuria and a decreased estimated GFR (<60 mL/min/1.73 m2) are both accompanied by a significant increase in cardiovascular (CV) risk. Chronic kidney disease can develop all over the cardiorenal continuum and its presence in hypertensive patients with already developed CV disease contributes to a further increase in the development of events and death. Renal protection will in turn obtain CV protection and the treatment to be used is similar to that employed to prevent or to treat established CV disease.
Journal
European Heart Journal – Oxford University Press
Published: Jul 28, 2011
Keywords: Hypertension Chronic kidney disease Cardiovascular disease Albuminuria Target organ damage