Poster session II
Abstract
Eur J Echocardiography Supplement, December 2010 doi:10.1093/ejechocard/jeq138 Thursday 9 December 2010, 14:00â18:00 GENERAL PRINCIPLES OF ECHOCARDIOGRAPHY P392 CRT optimisation: improving echocardiographic techniques by accommodating biological variability within different echocardiographic parameters PA. Pabari1; A. Kyriacou1; M. Moraldo1; B. Unsworth1; R. Baruah1; N. Sutaria1; A. Hughes1; J. Mayet1; DP Francis1 . 1 Imperial College London, London, United Kingdom Background: In optimisation of CRT (and even selection for implantation) we may underestimate the impact of beat-to-beat variation on echo measurements. This can be quantiï¬ed in the optimisation process, in which genuine small changes in cardiac function (signal) must be detected amongst beat-to-beat variation (noise). Methods and Results: To focus on biological variability we performed 2046 echo measurements in 11 patients by separate, replicate measurements at a series of interventricular delays of each potential optimisation modality including (i)3D SDI, (ii)aortic pre-ejection time, (iii)IVMD, (iv)LVOT VTI and (v)ECG. The equivalent of 31 optimisations per patient were performed. For single measurements at each setting, agreement between successive optimisations was low: 38% for SDI, 46% for aortic pre-ejection time, 30% for IVMD, 40% for LVOT VTI and 58% for ECG. Agreement between two methods,was similarly low, with agreement between optima being 20%. Guesswork would have