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Neuropsychological Sequelae in a Series of Patients with End-Stage Cystic Fibrosis: Lung Transplant Evaluation

Neuropsychological Sequelae in a Series of Patients with End-Stage Cystic Fibrosis: Lung... AbstractThere has been a relative absence of studies that examine the neuropsychological profiles of patients suffering from cystic fibrosis. Data are presented here for 18 individuals with end-stage cystic fibrosis who were also potential candidates for lung transplantation. Neuropsychological test results indicated a diversity of memory and executive control deficits, the most frequent of which were immediate and delayed free recall and retrieval impairments on a memory measure involving noncontextual verbal material. The majority of this sample of patients suffering from cystic fibrosis also exhibited clinically significant elevations on the Minnesota Multiphasic Personality Inventory-2 and Minnesota Multiphasic Personality Inventory-Adolescent (MMPI-2/MMPI-A), which are suggestive of heightened levels of psychological distress (e.g., depressive symptomatology) and multiple somatic complaints. These findings are discussed in light of factors associated with end-stage cystic fibrosis. Implications for clinical practice and future research are also provided. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Clinical Neuropsychology Oxford University Press

Neuropsychological Sequelae in a Series of Patients with End-Stage Cystic Fibrosis: Lung Transplant Evaluation

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References (18)

Publisher
Oxford University Press
Copyright
© Published by Oxford University Press.
ISSN
0887-6177
eISSN
1873-5843
DOI
10.1093/arclin/15.1.59
Publisher site
See Article on Publisher Site

Abstract

AbstractThere has been a relative absence of studies that examine the neuropsychological profiles of patients suffering from cystic fibrosis. Data are presented here for 18 individuals with end-stage cystic fibrosis who were also potential candidates for lung transplantation. Neuropsychological test results indicated a diversity of memory and executive control deficits, the most frequent of which were immediate and delayed free recall and retrieval impairments on a memory measure involving noncontextual verbal material. The majority of this sample of patients suffering from cystic fibrosis also exhibited clinically significant elevations on the Minnesota Multiphasic Personality Inventory-2 and Minnesota Multiphasic Personality Inventory-Adolescent (MMPI-2/MMPI-A), which are suggestive of heightened levels of psychological distress (e.g., depressive symptomatology) and multiple somatic complaints. These findings are discussed in light of factors associated with end-stage cystic fibrosis. Implications for clinical practice and future research are also provided.

Journal

Archives of Clinical NeuropsychologyOxford University Press

Published: Jan 1, 2000

Keywords: cystic fibrosis pulmonary disease medical disease neuropsychology young adults

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