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S. Lemmen, H. Häfner, S. Kotterik, Rudolf Lütticken, R. Töpper (2000)
Influence of an Infectious Disease Service on Antibiotic Prescription Behavior and Selection of Multiresistant PathogensInfection, 28
B. Byl, P. Clevenbergh, F. Jacobs, M. Struelens, F. Zech, A. Kentos, J. Thys (1999)
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J. Gómez, S. Cavero, J. Cardona, M. Núñez, J. Gómez, M. Canteras, M. Valdés (1996)
The influence of the opinion of an infectious disease consultant on the appropriateness of antibiotic treatment in a general hospital.The Journal of antimicrobial chemotherapy, 38 2
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American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients.Critical care medicine, 25 11
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Programmatic role of the infectious diseases physician in controlling antimicrobial costs in the hospital.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 24 3
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Platzer Roger, C. Martín, M. Taurel, J. Fournier, I. Nicole, M. Carles, Mondain, E. Fontas, F. Bertrand, C. Pradier, F. Vandenbos, P. Dellamonica (2002)
[Motives for the prescription of antibiotics in the emergency department of the University Hospital Center in Nice. A prospective study].Presse medicale, 31 2
U. Flúckiger, Werner Zimmerli, Hugo Sax, Reno Frei, Andreas Widmer (2000)
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Evelyn Lo, K. Rezai, A. Evans, M. Madariaga, Martin Phillips, Wahab Brobbey, D. Schwartz, Yue Wang, R. Weinstein, G. Trenholme (2004)
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A. Erbay, H. Bodur, E. Akıncı, Aylin Çolpan (2005)
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(2000)
Short-term impact of systematic infectiology consultation on antibiotic use in an intensive care unit.
M. Levy, M. Fink, J. Marshall, E. Abraham, D. Angus, Deborah Cook, Jonathan Cohen, S. Opal, J. Vincent, G. Ramsay (2003)
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions ConferenceCritical Care Medicine, 31
I. Gould (2002)
Antibiotic policies and control of resistanceCurrent Opinion in Infectious Diseases, 15
Objectives: Several studies have reported that infectious diseases (ID) consultations improve the quality of antibiotic prescription, providing adherence is adequate. The aim of this study is to determine the factors associated with adherence to such therapeutic advice.Patients and methods: We conducted a prospective study in two intensive care units (ICUs) over a 6 month period. Systematic bedside diagnostic and therapeutic ID advice was delivered for all patients receiving antibiotic therapy.Results: A total of 381 consultations for 195 patients were recorded, 244 (64%) in ward A and 137 (36%) in ward B. The median SAPS score was 45 and the mortality rate was 23%. Infections accounted for 220 (58%) admissions. A diagnostic discrepancy between ID and intensive care specialists was noted in 125 (33%) cases. The ID specialist advised continuation of the same antibiotic therapy in 138 (36%) cases, a change in 154 (41%) and withdrawal in 89 (23%). Adherence to ID therapeutic advice was recorded for 326 (86%) cases. Multivariate analysis identified two factors independently associated with adherence: ward B [odds ratio (OR), 4.9; 95% confidence interval (CI), 2.0–12.1] and proposition to pursue the same therapy (OR, 4.8; 95% CI, 1.6–14.5).Conclusions: Patients' characteristics and antibiotic therapy modalities do not influence adherence to ID consultation. In contrast, the ward and its characteristics play a major role in adherence to ID advice.
Journal of Antimicrobial Chemotherapy – Oxford University Press
Published: Mar 31, 2006
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