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suggests that negative feedback is a general mechanism used in signaling systems to align dose-responses and thereby increase the fidelity of information transmission . ...
, and (3) an excitable circuit constituted by two interlinked positive and negative feedback loops. (Right) Dependence of mutual information (MI) with the number of units (N) for each of these systems ...
environments frequently overlap, creating circumstances in which medically important pathogens and their mosquito vectors thrive to enhance the rate of transmission and epidemic outbreaks. Although quantifying ...
, and so that could explain the lack of negative responses. Individuals may also have been too kind to say bad things about the approach. Alternatively, they may have wanted to gather more information before ...
was used as a metric to argue that negative feedback enables dose-response alignment and enhances information transmission in the pheromone pathway in yeast [13]. Similarly, MI was used to estimate time ...
+ concentration in pollen cells negatively regulate ROP1 activity via a feedback mechanism (Yan et al., 2009). In addition to the regulatory factors that affect pollen Ca2+ concentration, sucrose, biosynthesis ...
of sym1D mutant, thanks to the high degree of conservation from yeast to human. The pathological mutations of human MPV17 are deleterious in yeast : they cause an OXPHOS- negative phenotype and result ...
to produce the ultimate yeast genome will irreversibly connect the dots between our improved understanding of the fundamentals of a complex cell containing its DNA in a specialised nucleus and the application ...
, 1968; Shen-Miller, 1973). Fidelity of signal transmission through noisy channels can be improved by feedback , indicating that the signal has been received. In plants, simple feedback loops using both ...
, there was limited inhibition of parasite transmission to mosquitoes [22], suggesting the need for improved vaccine formulations. Here, we describe a novel platform that incorporates sexual-stage malaria vaccine ...
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