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SF Gilbert (2003)
Developmental Biology
JMW Slack (2002)
C. H. Waddington: The last Renaissance biologistNature Reviews Genetics, 3
W. Schull, C. Waddington (1968)
Towards a Theoretical BiologyNature, 218
E. Wehmeier (2004)
Versuche zur Analyse der Induktionsmittel bei der Medullarplatteninduktion von UrodelenWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 132
CH Waddington (1961)
Genetic assimilationAdvances in Genetics, 10
R. Winther (2006)
Parts and Theories in Compositional BiologyBiology and Philosophy, 21
A. Robertson (1977)
Conrad Hal Waddington, 8 November 1905 - 26 September 1975Biographical Memoirs of Fellows of the Royal Society
E Wehmeier (1934)
Versuche zur Analyse der Induktionmittel bei der Medullar-Platteninduktion von UrodelenRoux’ Archiv, 152
C. Waddington (1964)
New patterns in genetics and development
J. Holtfreter (1951)
Some aspects of embryonic induction.Growth, Suppl 10
CH Waddington (1969)
Behind Appearance: A Study of the Relations Between Painting and the Natural Sciences in this Century
A. Wilkins (2008)
Waddington’s Unfinished Critique of Neo-Darwinian Genetics: Then and NowBiological Theory, 3
M. Siegal, A. Bergman (2002)
Waddington's canalization revisited: Developmental stability and evolutionProceedings of the National Academy of Sciences of the United States of America, 99
A. Turing (1952)
The chemical basis of morphogenesisBulletin of Mathematical Biology, 52
Scott Gilbert (1991)
Induction and the origins of developmental genetics.Developmental biology, 7
C. Waddington (1969)
Art as Response to Science. (Book Reviews: Behind Appearance. A Study of the Relations between Painting and the Natural Sciences in This Century)Science
Scott Gilbert (1997)
Salome Gluecksohn Waelsch
J. Slack (2002)
Conrad Hal Waddington: the last Renaissance biologist?Nature Reviews Genetics, 3
C. Waddington (1975)
The evolution of an evolutionist
C. Waddington, R. Cowe (1969)
Computer simulation of a mulluscan pigmentation pattern.Journal of theoretical biology, 25 2
Claudio Stern (2000)
Conrad H. Waddington's contributions to avian and mammalian development, 1930-1940.The International journal of developmental biology, 44 1
Conrad Waddington (1957)
The strategy of the genes
L. Wolpert (1997)
Principles of Development
AS Wilkins (2008)
Waddington’s unfinished critique of neo-Darwinian genetics: Then and nowTheoretical Biology, 3
M. Wake (2008)
Organisms and OrganizationBiological Theory, 3
G. Moment, S. Gould (1978)
Ontogeny and PhylogenyBioScience
C. Waddington (1941)
Evolution of Developmental SystemsNature, 147
AM Turing (1952)
The chemical basis of morphogenesisPhilosophical Transactions of the Royal Society B, 237
SF Gilbert (1991)
A Conceptual History of Modern Embryology
C. Waddington (1943)
Organisers and genes.
C. Waddington (2018)
"Experiments on the Development of Chick and Duck Embryos, Cultivated in vitro" (1932), by Conrad Hal Waddington
B. Goodwin (1963)
Temporal organization in cells
C. Waddington, J. Needham, J. Brachet (1936)
Studies on the Nature of the Amphibian Organization Centre. III.--The Activation of the EvocatorProceedings of The Royal Society B: Biological Sciences, 120
SF Gilbert (1997)
Jewish Women in America: An Historical Encyclopedia
F. Crick, P. Anderson (1989)
WHAT MAD PURSUIT. A Personal View of Scientific Discovery.
C. Waddington (1939)
An Introduction to Modern Genetics
M. Laubichler, H. Rheinberger (2004)
Alfred Kühn (1885-1968) and developmental evolution.Journal of experimental zoology. Part B, Molecular and developmental evolution, 302 2
E. Hadorn, U. Mittwoch (1961)
Developmental genetics and lethal factorsThe American Journal of the Medical Sciences, 242
AN Whitehead (1929)
Process and Reality
A Wilkins (2002)
The Evolution of Genetic Pathways
MH Wake (2008)
Organisms and organizationTheoretical Biology, 3
L. Speybroeck (2002)
From Epigenesis to EpigeneticsAnnals of the New York Academy of Sciences, 981
CH Waddington (1932)
Experiments on the development of chick and duck embryos cultivated in vitroPhilosophical Transactions of the Royal Society London B, 221
CH Waddington, J Needham, J Brachet (1936)
The activation of an evocatorProceedings of the Royal Society London B, 120
L. Wolpert (1969)
Positional information and the spatial pattern of cellular differentiation.Journal of theoretical biology, 25 1
C. Waddington (1940)
The genetic control of wing development inDrosophilaJournal of Genetics, 41
Conrad Hal Waddington (1905–1975) was a British developmental biologist who mainly worked in Cambridge and Edinburgh, but spent the late 1930s with Morgan in California learning about Drosophila . He was the first person to realize that development depended on the then unknown activities of genes, and he needed an appropriate model organism. His major experimental contributions were to show how mutation analysis could be used to investigate developmental mechanisms in Drosophila , and to explore how developmental mutation could drive evolution, his other deep interest. Waddington was, however, predominantly a thinker, and set out to provide a coherent framework for understanding the genetic bases of embryogenesis and evolution, developing his ideas in many books. Perhaps his best-known concept is the epigenetic landscape: here a ball rolls down a complex valley, making path choices. The rolling ball represents a cell's development over time, while the topography represents the changing regulatory environment that controls these choices. In its later forms, the role of each feature in the landscape was controlled by the effects of sets of interacting genes, an idea underpinning contemporary approaches to systems biology. Waddington was the first developmental geneticist and probably the most important developmental biologist of the pre-molecular age.
Biological Theory – MIT Press
Published: Aug 1, 2008
Keywords: developmental genetics; epigenetic landscape; epigenetics; evolution; genetic assimilation; induction crisis; systems biology; theoretical biology; Waddington
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