Neoplasms
Definition: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Articles related to this term...
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The Co-Action Of Estrogen In The Induction Of Tumors Of The Mouse Uterus Treated With 20-Methylcholanthrene Abstract
Proceedings of the American Association for Cancer Research
Over 200 young mature and mature CF1 mice were ovariectomized and their uterine horns implanted bilaterally with circa 2 mg methylcholanthrene (MCA) by trocar. Subcutaneous injections of 20 mcg diethylstilbestrol in 0.05 ml oil were then made 3x weekly in equ...
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Observations On Rats Treated With The Sex Hormones Estrin And Testosterone.
The American journal of cancer
The occurrence of 3 tar cancers of the skin, 1 uterine cancer, and 1 gastric cancer are reported in rats fed with an estrin product obtained from pregnancy urine. A tar cancer is recorded in 1 control rat. Whereas in rats injected with estrone for long perio...
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Carcinoma Mammae Occurring In A Male Mouse Under Continued Treatment With Oestrin.
The American journal of cancer
Several studies have proven the connection between ovarian activity, or treatment with estrogens, and breast cancer in laboratory animals. This article presents the results of an experiment conducted on 130 male mice of no particular strain, of which 20 had b...
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Metaplasia Of Uterine Epithelium Produced In Rats By Prolonged Administration Of Oestrin.
The American journal of cancer
11 castrate female rats were treated with intrauterine injections of a solution of estrone in corn oil; 11 additional castrate female rats were administered with the same solution by daily subcutaneous injections. Vaginal smears in both groups showed continuo...
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Relation Of Nursing To The Extra-Chromosomal Theory Of Breast Cancer In Mice.
The American journal of cancer
This study investigates the effect of nursing on the incidence of breast tumors in mice. The A inbred high-cancer line was used as control and newborn young of A stock mothers were removed and fostered by females of the low-tumor C57 Black or CBA lines. It w...
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The Effect Of Androgens And Estrogens On Spontaneous Benign Mammary Tumors In The Rat.
The American journal of cancer
This article studies spontaneous benign mammary tumors in 97 female and male rats. All animals were observed until death and in every instance the tumors were examined and measured. In the 1st series of experiments autotransplants and homotransplants were do...
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Further Investigations On The Origin Of Tumors In Mice. Iii. On The Part Played By Internal Secretion In The Spontaneous Development Of Tumors.
The Journal of cancer research
Castration of female mice below 6 months of age resulted in a marked reduction of tumor incidence, from between 60-70% in control mice to 9% in castrated mice. Although majority of the tumors appeared during the 1st age period in the controls, they were delay...
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Mammary Neoplasms Of The Bitch.
The Journal of comparative pathology and therapeutics
In this paper, the interrelationships of the neoplasms of the canine mammary gland are investigated. These neoplasms are a group of tumors of a great variety of histological structure and sometimes of uncertain histogenesis. Particular attention is given to ...
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On The Proliferative Changes Taking Place In The Epithelium Of Vagina And Cervix Of Mice With Advancing Age And Under The Influence Of Experimentally Administered Estrogenic Hormones.
The American journal of cancer
This study describes the gradual changes which take place in the epithelium of vagina and cervix of mice from early to advanced age, with and without the stimulation of estrogen and other hormones, and the eventual transition from normal growth processes to pr...
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The Effect Of The Sex Hormones On The Growth Of Transplanted Mammary Adenofibroma In Rats.
The American journal of cancer
This study reports on an experiment involving normal female rats, castrates of both sexes, and estrogen-injected castrates to determine whether or not estrogenic hormones are capable of influencing transplanted adenofibroma. A total of 469 normal and castrate...
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Diffuse Bone Metastases, Prevalently Blastic, Of Adenocarcinoma Of The Colon
La Radiologia medica
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Resistance-Suppressing Activity Of Transformed Syrian Hamster Cells And Their Ability To Metastasize
Biulleten' eksperimental'no? biologii i meditsiny
Hamster embryo cells spontaneously transformed in vitro (HETr) with low metastatic activity were not capable to depress natural antitumor resistance in vivo in contrast to some other lines of Syrian hamster tumor cells. The resistance, depressing and metastati...
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Incidence Of Bone Metastases From Breast Carcinoma: Possibilities Of Radiotherapy
La Radiologia medica
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Mechanisms Of Localization And Increase Of Metastases In Bone Tissue
La Radiologia medica
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Possible Participation Of Endogenous Mmtv Virus In Chemical Carcinogenesis Of Mouse Mammary Glands
Biulleten' eksperimental'no? biologii i meditsiny
A study was made of the effect of immunization with formalinized MMTV on mammary tumor incidence in BALB/c mice exposed to dimethylbenzanthracene. In mice immunized with MMTV, the incidence of mammary tumours was significantly lower and the latent period longe...
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Stimulating Action Of Estradiol Dipropionate On Uterine Sarcomagenesis Induced By 1,2-Dimethylhydrazine In Mice
Biulleten' eksperimental'no? biologii i meditsiny
CBA female mice received weekly subcutaneous injections of 1,2-dimethylhydrazine (1,2-DMH) in a dose of 8 mg/kg for 10 weeks (group 1). In groups 2,3 and 4 1,2-DMH plus estradiol dipropionate were administered for 10, 20 or 25 weeks, respectively. The incidenc...
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Role Of Prolactin In The Development Of Mammary Gland Tumors Induced By Dimethylbenzanthracene
Biulleten' eksperimental'no? biologii i meditsiny
The action of high prolactin content on dimethylbenzanthracene-induced mammary carcinoma was studied in rats with varying bodily content of estrogens. It was found that the high content of endogenous prolactin in rats provoked by ligation of the hypophyseal pe...
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Membrane Antigens Of Transformed And Tumor Cells Of Hamsters
Biulleten' eksperimental'no? biologii i meditsiny
Normal membrane antigens to tumour and in vitro transformed tissue cultures of Syrian hamster cells were comparatively studied in cross-adsorption experiments. It was found that each cell strain has an individual profile of normal membrane antigens with charac...