Granulosa Cell Tumor

Granulosa Cell Tumor

Definition: A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.

Endocrine System Diseases > Endocrine Gland Neoplasms > Ovarian Neoplasms > Granulosa Cell Tumor

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