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Trisomy for autosome No. 19 in mouse embryos (days 12-14 of development) was accompanied by a 1.5-fold increase in specific activity of cytoplasmic glutamate-oxaloacetate transaminase whose gene is known to be located in the 19th chromosome. Specific activity of cytoplasmic malate dehydrogenase remained unchanged under these circumstances, while activity of lactate dehydrogenase increased 1.1-fold.

Effect of gene dose on cytoplasmic glutamate-oxaloacetate transaminase in embryonic mice with trisomy 19

Abstract

Trisomy for autosome No. 19 in mouse embryos (days 12-14 of development) was accompanied by a 1.5-fold increase in specific activity of cytoplasmic glutamate-oxaloacetate transaminase whose gene is known to be located in the 19th chromosome. Specific activity of cytoplasmic malate dehydrogenase remained unchanged under these circumstances, while activity of lactate dehydrogenase increased 1.1-fold.

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Effect of gene dose on cytoplasmic glutamate-oxaloacetate transaminase in embryonic mice with trisomy 19

Vaĭsman, B. L.; Dyban, A. P.; Udalova, L. D.
Biulleten' eksperimental'noĭ biologii i meditsiny
MEDLINE Abstracts – May 1, 1981

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