The effect of acute hypoxia on mouse embryogenesis and its influence on the sex ratio in the progeny was studied. On the 7th--10th day of pregnancy mice were subjected to hypoxia at 230 mm HG for 3 hours. They were sacrificed on the 18th day of pregnancy, and gonads of their embryos were taken for investigation. The sex ratio was determined as the ratio of the number of males to that of females. It has been shown that acute hypoxia on the 7th--10th days of pregnancy, resulting in high mortality of adult animals, had no substantial effect on the embryonic development. No selective death of the embryos of either sex was observed both in experimental and control groups.
Effect of acute hypoxia on embryonal death and the sex ratio of the progeny
Abstract
The effect of acute hypoxia on mouse embryogenesis and its influence on the sex ratio in the progeny was studied. On the 7th--10th day of pregnancy mice were subjected to hypoxia at 230 mm HG for 3 hours. They were sacrificed on the 18th day of pregnancy, and gonads of their embryos were taken for investigation. The sex ratio was determined as the ratio of the number of males to that of females. It has been shown that acute hypoxia on the 7th--10th days of pregnancy, resulting in high mortality of adult animals, had no substantial effect on the embryonic development. No selective death of the embryos of either sex was observed both in experimental and control groups.Preview Only. This article cannot be rented because we do not currently have permission from the publisher.
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Effect of acute hypoxia on embryonal death and the sex ratio of the progeny
Udalova, L. D.
Biulleten' eksperimental'noĭ biologii i meditsiny
MEDLINE Abstracts – Jan 1, 1978
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