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be different resulting in the striatal atrophy pattern observed here. Cerebellar pathology in XDP In addition to the well-studied striatum, recent imaging studies revealed reductions of cerebello-thalamic ...
Abstract Dystonias are a heterogeneous group of disorders which are known to have a strong inherited basis. This review details recent advances in our understanding of the genetic basis of dystonias ...
and behavior. New mechanotransduction interactions are being discovered, but some known mechanisms include elements that connect the cell to its environment through focal adhesions[1, 2], the actin cytoskeleton ...
]. TNKSs can interact with Axin, mediate its parsylation and then stimulate its degradation through the ubiquitin-proteasome pathway, therefore promoting Wnt/β-catenin signaling [23]. TNKSs are widely ...
understanding of pathologic mineralization/ossification. Significance statement Platelet-derived growth factor alpha (PDGFRα) expression highlights distinct perivascular subpopulations of adipose stroma ...
vertebrates, including specification of myeloid lineages, which can be coupled with optical transparency and genetic tractability to allow for high resolution in vivo imaging of innate immune processes [40, 41 ...
expression, and intracellular Ca2+ concentration. Furthermore, experimental results also indicate that ATP11B regulated synaptic plasticity in hippocampal neurons through the MAPK14 signaling pathway ...
highlight that EIF5A2 contributes to CD133(+) cancer cells maintenance in HCC through the c-Myc/miRNA29b pathway, suggesting a potential CSCs-specific therapeutic target, EIF5A2, for the treatment of HCC ...
identified their transcriptional regulation through reciprocal promoter occupancy in CD15+ MB stem cells. Our work demonstrates the application of stem cell data gathered from genomic platforms to guide ...
of the transabdominal phase of testicular descent during fetal development by acting on gubernaculum through the activation of its specific relaxin family receptor 2 (RXFP2); indeed, mutations in INSL3 and RXFP2 genes ...
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