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, Australia Study design : Systematic review. Objectives: To provide a quantitative analysis of all randomized controlled trials designed to determine the effectiveness of physical interventions for people ...
with registration-based techniques. Fully automated analysis methods, including segmentation of grey matter and intramedullary lesions, will facilitate the use of spinal cord atrophy in trial designs ...
in quantitative measures using diffusion and magnetization-weighted imaging after recovery from the myelitis. Additionally, these spinal cord MRI metrics show clinical relevance in terms of pain and disability ...
. Download: PPT PowerPoint slide PNG larger image TIFF original image Fig 2. Trial design : Study timeline showing each study visit and the duration of the entire study. tSCS = Transcutaneous spinal cord ...
). Open in new tabDownload slide Open in new tabDownload slide Cervical spinal cord injury, Spinal cord injury, Preclinical, Oligodendrocyte progenitor cell, Human embryonic stem cell, Clinical trial ...
of stem cells into damaged spinal cord regions is commonly used [5, 6]. However, this route is hard to be translated to clinical trials since it might induce secondary injuries to the spinal cord [7 ...
BackgroundIMI2-PainCare-BioPain-RCT3 is one of four similarly designed clinical studies aiming at profiling a set of functional biomarkers of drug effects on the nociceptive system that could serve ...
for the treatment of a variety of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and spinal cord injury (SCI), has recently reached the clinical trial stage with several phase I or phase ...
) and Spectroscopy (MRS) scan of the brain and spinal cord ; clinical , cognitive, mood and speech assessments and collection of a blood sample. Primary outcome measures, informed by previous neuroimaging studies ...
the methodology of studies using tSCS to generate motor activity in persons with spinal cord injury (SCI) and to appraise the quality of included trials . Methods A systematic search for studies published until May ...
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