Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Quantitative evaluation of the administrated dose affecting image quality in myocardial perfusion SPECT

Quantitative evaluation of the administrated dose affecting image quality in myocardial perfusion... BACKGROUND: Myocardial perfusion imaging (MPI) can provide the valuable cardiac functions.Image quality in nuclear medicine tomography is critically dependent on the activity administered into patients. OBJECTIVE: This study was designed to evaluate the optimum injected dose of 99mTc-MIBI for quantitative assessment of image quality as compared with standard injected dose used for that purpose. METHODS: The image quality parameters (Contrast, relative noise and contrast to noise ratio) were determined in 32 patients (21 male, 11 female, age 45–60 y) with weight 60 ± 15 kg. Patients were classified into four groups; each one consisted of 8 patients. The first group received 370 MBq, the second one received 555 MBq, the third group received 740 MBq and the last group received 925 MBq. RESULTS: Qualitative assessments of the images revealed equivalent scintigraphic patterns in all patients. There was a significant difference in the image contrast. The image contrast in the 370 MBq group was greater than other groups. The image noise between the four groups was significantly different. It increased with injected dose reduction. Contrast to noise ratio (CNR) was significantly different between 370 MBq and other groups. CONCLUSION: It is concluded that results from the first group which received 370 MBq are sufficiently similar to those of the fourth group (standard group) which received 925 MBq. Consequently,accurate estimations of differential cardiac functions are possible with the 370 MBq dose. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of X-Ray Science and Technology IOS Press

Quantitative evaluation of the administrated dose affecting image quality in myocardial perfusion SPECT

Download PDF
9 pages

Loading next page...
 
/lp/ios-press/quantitative-evaluation-of-the-administrated-dose-affecting-image-B7E08kpPw3

References (20)

Publisher
IOS Press
Copyright
Copyright © 2014 by IOS Press, Inc
ISSN
0895-3996
eISSN
1095-9114
DOI
10.3233/XST-140443
pmid
25080119
Publisher site
See Article on Publisher Site

Abstract

BACKGROUND: Myocardial perfusion imaging (MPI) can provide the valuable cardiac functions.Image quality in nuclear medicine tomography is critically dependent on the activity administered into patients. OBJECTIVE: This study was designed to evaluate the optimum injected dose of 99mTc-MIBI for quantitative assessment of image quality as compared with standard injected dose used for that purpose. METHODS: The image quality parameters (Contrast, relative noise and contrast to noise ratio) were determined in 32 patients (21 male, 11 female, age 45–60 y) with weight 60 ± 15 kg. Patients were classified into four groups; each one consisted of 8 patients. The first group received 370 MBq, the second one received 555 MBq, the third group received 740 MBq and the last group received 925 MBq. RESULTS: Qualitative assessments of the images revealed equivalent scintigraphic patterns in all patients. There was a significant difference in the image contrast. The image contrast in the 370 MBq group was greater than other groups. The image noise between the four groups was significantly different. It increased with injected dose reduction. Contrast to noise ratio (CNR) was significantly different between 370 MBq and other groups. CONCLUSION: It is concluded that results from the first group which received 370 MBq are sufficiently similar to those of the fourth group (standard group) which received 925 MBq. Consequently,accurate estimations of differential cardiac functions are possible with the 370 MBq dose.

Journal

Journal of X-Ray Science and Technology – IOS Press

Published: Jan 1, 2014

There are no references for this article.