Degeneration speed of corticospinal tract in patients with cerebral infarct

Dong Gyu Kim; Young Hwan Ahn; Woo Mok Byun; Tae Gun Kim; Dong Suk Yang; Sang Ho Ahn; Yoon Woo Cho; Sung Ho Jang

$Objectives: Diffusion tensor image tractography (DTT) could be useful for exploring the state of the corticospinal tract (CST) at the level of the subcortical white matter. The purpose of this study was to demonstrate the speed of degeneration of the CST in patients with cerebral infarct, using DTT. Design: Two patients with middle cerebral artery territory infarct were recruited for this study. DTT was performed 5 times with an interval of 7 days, starting at 2 days after onset, using a 1.5-T system with a synergy-L Sensitivity Encoding head coil. The termination criteria used were fractional anisotrophy < 0.3, 0.2, 0.1, respectively, and an angle change > 45°. Results: Detection of CST degeneration began at the 9 day DTT in both patients. The most rapid CST degeneration was noted for 7 days at 16 days from onset. We did not detect any tract in the affected hemisphere of both patients at the 23-day DTT. Conclusions: We demonstrated that CST degeneration begins before 9 days from onset and progresses rapidly in patients with middle cerebral artery territory infarct. It seems that the CST degeneration began earlier than expected.$

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Degeneration speed of corticospinal tract in patients with cerebral infarct

Kim, Dong Gyu; Ahn, Young Hwan; Byun, Woo Mok; Kim, Tae Gun; Yang, Dong Suk; Ahn, Sang Ho; Cho, Yoon Woo; Jang, Sung Ho

Follow NeuroRehabilitation , Volume 22 (4) IOS Press – Jan 1, 2007

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Degeneration speed of corticospinal tract in patients with cerebral infarct

Kim, Dong Gyu; Ahn, Young Hwan; Byun, Woo Mok; Kim, Tae Gun; Yang, Dong Suk; Ahn, Sang Ho; Cho, Yoon Woo; Jang, Sung Ho

Follow NeuroRehabilitation , Volume 22 (4) IOS Press – Jan 1, 2007

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