N-(4-Acetylphenyl)acetohydroxamic acid
Abstract
<h2>Acta Crystallographica Section C</h2><h3>Crystal Structure Communications</h3><h3>0108-2701</h3> <h2>research papers (organic compounds)</h2> Volume 43 Part 3 Pages 493-495 March 1987 <h2> N -(4-Acetylphenyl)acetohydroxamic acid</h2> D. R. Powell and D. van der Helm Acta Cryst. (1987). C43, 493-495 / N-(4-Acetylphenyl)acetohydroxamic Acid BY DOUGLAS R. POWELL AND DICK VAN DER HELM Department of Chem&try, University of Oklahoma, Norman, OK 73019, USA (Received l0 March 1986; accepted 17 September 1986) Abstract. C10HuNOs, Mr= 193.20, monoclinic, P2~/n, a=23.539(5), b=8.473(2), c=9.540A, fl=99.44(2)°, V=1876.9 (7) A3, z=8, Dx- 1.367 gcm-3, Ni-filtered Cu K~ 2 -- 1.5418 A, /t -- 7-55 cm-~, F(000) = 816, T= 138 (2) K, R = 0.057 for 3018 data. The hydroxamate groups of the two crystallographically unique molecules have a trans conformation. Both molecules are roughly planar and have similar molecular conformations and identical dimensions, which are compared with those of other N-substituted acetohydroxamic acids. The molecules are linked by two intermolecular hydrogen bonds with lengths 2.631 (2)and 2.636 (2)A. Introduction. Under iron-limiting conditions, micro- organisms produce a variety of small chelating agents which solubilize ferric iron in the environment and transport the iron to the cell. Many of these metabolites chelate the iron through hydroxamic acid groups. Both naturally occurring