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Background: Hypoxia can induce tissue injury, including apoptosis of endothelial cells . However, little is known about the effects of hypoxia on endothelial cell function . We assessed the effects ...
Summary. As the cells forming the luminal vascular surface, endothelium is exposed to alterations in the vascular microenvironment, such as hypoxaemia. In this report we demonstrate that hypoxia ...
villous explants of noncomplicated placentae and BeWo cells were subjected to hypoxia . The effect of placental hypoxic-conditioned medium (HCM) on intraluminal-induced contraction and endothelial barrier ...
stroke. Here we investigated the expression of P2Y1R in primary cultured brain endothelial cells and its relation to the maintenance of BBB function . Results show that following in vitro hypoxia ...
proliferation, migration, and autophagy; and increased apoptosis. Furthermore, the microRNA-195-3p inhibitor partially reversed the effects of hypoxia -induced injury of human umbilical vein endothelial cells ...
Previous studies have found that microRNA-126 (miR-126) overexpression can exert beneficial effects on endothelial function and angiogenesis. The role of miR-126 was previously reported ...
and only partially identified pleiotropic effects . This study aimed to analyze impacts of atorvastatin and synthetic peptide PCSK9i on bioenergetics and function of microvascular endothelial cells ...
CoCl2‐Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors 1, ,† 1,† 1 1 1 Barbara Kutryb‐Zajac * , Ada Kawecka , Alicja ...
The aim of this study was to investigate hypoxia effects on vascular endothelial growth factor (VEGF) and its receptors VEGFR-1 and VEGFR-2 in human umbilical vein endothelial cells (HUVEC ...
oxygenation. A key role in flow regulation is played by conducted responses, which are generated and propagated by endothelial cells and signal upstream arterioles to dilate in response to local hypoxia ...
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