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The requirement for delivery by injection is currently a limitation for the use of biologic drugs such as antibodies. In this Review, Mitragotri and colleagues discuss advances made in non - invasive ...
). Pulmonary delivery is an attractive non - invasive alternative route of administration for local and systemic delivery of biologics with immense potential to treat various diseases, including diabetes, cystic ...
and impracticality of these procedures has, however, prompted the development of novel drug delivery strategies including the intranasal route of administration. This represents a non - invasive way to achieve the CNS ...
. In the process of radiation treatment, radiobiological responses of tumor and normal tissue in patients are monitored non - invasively by a variety of techniques including imaging, biological methods and biochemical ...
—the first treatment stage of glioblastoma. Exosomes are among non - invasive drug delivery methods and have emerged as a natural drug delivery vehicle with high biological barrier penetrability ...
clinical products are mainly delivered via parenteral route with inferior convenience. Lung is an attractive non - invasive alternative passage for systemic administration of biologics with numerous ...
on the analysis of biopsies, which provide limited information. Non - invasive monitoring of gene delivery and expression is a very attractive approach as it can be repeated over time in the same patient to provide ...
and increasing societal cost. The crucial point of the non - invasive therapeutic strategy for neurological disorder treatment relies on the drugs’ passage through the blood-brain barrier (BBB). Indeed ...
unusual routes due to RNA instability in biological medium. Lung delivery provides extensive area of absorption and alveolar deposition, non - invasiveness and local action. However, biological barriers ...
BackgroundLong non -coding RNAs are important regulators of gene expression and diverse biological processes. Their aberrant expression contributes to a verity of diseases including cancer development ...
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