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Severe hemophagocytic syndrome developing after treatment initiation for disseminated Mycobacterium tuberculosis: Case report and literature review

Severe hemophagocytic syndrome developing after treatment initiation for disseminated Mycobacterium tuberculosis: Case report and literature review

Abstract

We describe a case of a young male with disseminated tuberculosis and severe secondary hemophagocytic syndrome. He presented with symptoms of tuberculosis and Mycobacterium tuberculosis was diagnosed. Later, while on anti-tuberculous treatment, he developed pancytopenia and bone marrow aspirate showed large macrophages with increased phagocytosis of mature and immature blood elements typical of hemophagocytic syndrome.
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