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with inflammatory responses in the myocardium. Neutrophils feature prominently in this inflammatory component of postischemic injury . Ischemia – reperfusion prompts a release of oxygen free radicals, cytokines ...
. Reperfusion induced injury : manifestations, mechanisms, and clinical relevance. Cardiovasc Res . 1992 ; 26 : 101 –108 [4] Jordan JE , Zhao ZQ, Vinten-Johansen J. The role of neutrophils in myocardial ischemia ...
injury . Current data are highly suggestive of a deleterious role of the neutrophil in organ reperfusion and justify consideration of the clinical investigation of neutrophil inhibitors in patients ...
recruitment. The evidence weighs against a pivotal role of neutrophils as a causal factor in most forms of ischemia - reperfusion injury . An exception may be microvascular injury and capillary plugging leading ...
ischemia and reperfusion is at least par tially dependent upon adhesion of neutrophils to myocardial and endotheliai cells. Neutrophils are thought to contribute to reperfusion injury by two mechanisms ...
BRC 363 Basic Res Cardiol 97: 263 – 267 (2002) DOI 10.1007/s00395-002-0363-x LEUCOCY TES IN MYOCARDIAL ISCHEMIA / REPERFUSION David J. Lefer Do neutrophils contribute to myocardial reperfusion injury ...
, if administered before reperfusion .—Lefer, A. M.; Tsao, P. S.; Lefer, D. J.; Ma, X.‐1. Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia . FASEB J. 5: 2029–2034 ...
following reperfusion of ischemic myocardium. Proc Natl Acad Sci USA. 1987. p. 1404–1407 [4] Hansen PR . Role of neutrophils in myocardial ischemia and reperfusion . Circulation . 1995 ; 91 : 1872 –1885 [5 ...
important pathogenesis It is of interest, therefore, to myocardial develop ischemia / reperfusion injury . pharmacologic to inhibit adhesion to the endothelium. agents designed neutrophil to the P-selectin ...
Circulation LETTER TO THE EDITOR Letter by Wang Regarding Article, “Platelet Serotonin Aggravates Myocardial Ischemia / Reperfusion Injury via Neutrophil Degranulation” To the Editor: Wei Wang, MD We ...
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