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(a combination of vitamins C and E) and L -arginine treatment on renal failure in mice by measuring survival rate. The molecular changes were elucidated by determining endothelial tetrahydrobiopterin (BH4) levels ...
dysfunction occurs even when optimal donors are used and when short-term EP treatment is given. Increased renal superoxide production is not prevented by short-term EP therapy. IntroductionLiving related donor ...
filtration.Recent findingsPreclinical disease models of ischemic renal injury , including acute ischemia/reperfusion, thrombotic microangiopathy, and chronic renovascular disease, treated with exogenous VEGF ...
with chronic renal failure does not prevent CM-induced nephrotoxicity and does not affect endothelial dysfunction in the particular population studied by the authors, i.e. patients with coronary artery disease ...
, the observation that eNOS gene delivery prevents the aggravation of hypertension in renal failure animals further supports a pivotal role for NO in hypertension and endothelial dysfunction associated with chronic ...
mileu and leads to endothelial dysfunction , subsequent glomerular filtration barrier damage, and progressive renal injury . Chronic kidney disease (CKD), in turn, induces deleterious effects on lipid ...
the impact of global Sirt3 deficiency on renal endothelial cell phenotype and to investigate whether SIRT3 deficiency impacts on endothelial dysfunction and on the severity of renal injury induced ...
intermediate phenotype in the relationship between inflammation and CVD in ESRD patients. Table 1. Potential causes of endothelial dysfunction in ESRD Inflammation Retention of l ‐arginine inhibitors (ADMA ...
pathways leading to renal injury in acute renal ischaemia. Note that tubular epithelial cell injury is partly dependent on the development of localized endothelial dysfunction and diapedesis of inflammatory ...
aimed at targeting these CKD-associated disturbances, to possibly prevent progression of endothelial injury and thereby attenuate cardiovascular disease. ENDOTHELIAL DYSFUNCTION DURING CKD Dysfunctional ...
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