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of platelets to adherent leukocytes appears to contribute significantly to the platelet – vessel wall interactions elicited in many models of disease. Shear forces generated by the movement of blood through ...
arterial vessels . The role of the vWF-GPIb interaction in platelet adhesion is well known; that of the vWF-GPIIb/IIIa interaction has been more recently demonstrated through the use of monoclonal antibodies ...
. Erythrocytes leukocytes and platelets may adhere to the vessel wall in physiological or pathological conditions. PLATELET VESSEL WALL INTERACTIONS (1) Platelets playa major role in the control of the bleeding ...
platelets was studied in hamster arterioles (dorsal skinfold chamber) by intravital microscopy. Transient platelet – vessel wall interactions (PVWIs), firm platelet adhesion to the vessel wall , and vessel ...
with the arteriolar wall ( platelet - vessel wall interaction , PVWI) was assessed by intravital microscopy in skin muscle of awake hamsters. To understand the mechanisms of EDHF-induced platelet inhibition, we studied ...
, and not other leucocytes, appear to be essential for LPAg formation. Enhanced PMN– platelet interaction in the microcirculation may facilitate platelet adhesion to vessel walls and promote the formation ...
, I/R) largely reflects an infiltration of neutrophils, while other leukocyte populations appear to dominate the adhesive interactions with the vessel wall at 24 h of reperfusion. The influx of rolling ...
. Video microscopy has been used for observations of interactions between platelets and microvessel walls in vivo . Model approaches involve perturbations of the microcirculation since circulating platelets ...
ABSTRACT In this review, the authors summarize how platelets interact with subendothelium when the vessel wall is damaged or with intact endothelium in the inflammatory state. When subendothelium ...
of the materials released from these platelets affect the vessel wall . The initial platelet mass is transformed to a fibrin mass. There are compounds that inhibit the platelet release reaction, platelet aggregation ...
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