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tandem mass spectrometry (ESI-MS/MS) was used to determine phosphatidylcholine (PC), lysophosphatidylcholine (LPC), and sphingomyelin (SM) in lipid extracts of mucus specimens. Results Human and rodent ...
of phosphatidylcholine (PC) to lysophosphatidylcholine (L-PC) when both are applied to the apical surface of cultured EC monolayers, resulting in increased bacterial translocation (BT) and decreased transepithelial ...
ADS PubMed 30. Ehehalt R, Wagenblast J, Erben G, et al. . Phosphatidylcholine and lysophosphatidylcholine in intestinal mucus of ulcerative colitis patients. A quantitative approach ...
– 1444 . Google Scholar Crossref Search ADS PubMed WorldCat 47. Ehehalt R , Wagenblast J , Erben G , et al. Phosphatidylcholine and lysophosphatidylcholine in intestinal mucus of ulcerative colitis ...
of phospholipids, predominantly phosphatidylcholine (PC) and lysophosphatidylcholine (LPC).48 It is hypothesized that defective mucus leads to increased interactions between the epithelium and luminal antigens ...
of the intestinal barrier integrity is key in the initiation of IBD and its symptoms (Figure 1). Along with protein mucins, phosphatidylcholine is an essential component of mucus , which acts to block the entry ...
1 Introduction A large number of bacteria that are present in the intestine of mammals are attached to the surface of the intestinal mucosa, and they participate in host digestion, metabolism, immune ...
in the expression pattern of metabolic enzymes in the GI membrane can influence the intestinal first-pass metabolism.[8] Alterations in the composition and the location of the GI microbiota can change the exposure ...
. Among other metabolites, lysophosphatidylcholine (LPC; 18:1), phosphatidylcholine (PC; 36:6; 18:2/18:0; 16:0/18:1; 16:0/20:3; 16:0/20:4; 20:4/22:5), PE (P-16:0/22:6), sphingomyelin (SM; 32:0; 32:2; 33:2 ...
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