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deposition of drugs into the lungs, and better therapeutic effects at low doses and is self- administrable by the patients. Thus, there is a need for scientists to design more convenient pulmonary drug delivery ...
/10.1080/10717544.2017.1365395 RESEARCH ARTICLE Hierarchical pulmonary target nanoparticles via inhaled administration for anticancer drug delivery a a a a a a a a,b Rui Chen , Liu Xu , Qin Fan , Man Li ...
Administration of Prostacyclin Analogue–incorporated Nanoparticles Ameliorates the Development of Monocrotaline and Sugen-Hypoxia-induced Pulmonary Arterial Hypertension Satoshi Akagi, MD, PhD,* Kazufumi Nakamura ...
the pharmacokinetics and bioavailability of drugs . Large porous microparticles, and porous nanoparticle -encapsulated microparticles are the most promising carriers for achieving effective pulmonary deposition of inhaled ...
nanoparticles were produced by nanoprecipitation of an amphiphilic pegylated poly-ɛ-caprolactone/polyhydroxyethyl aspartamide graft copolymer. The obtained nanoparticles that showed a drug loading of 14.4 wt ...
Drug resistance and the harmful side effects accompanying the prolonged corticosteroid treatment of chronic pulmonary diseases prompted the development of more specific anti-inflammatory approaches ...
efficiencies of the selected macromolecules. Introduction The transmucosal modalities of drug administration (oral, nasal, pulmonary , ocular…) represent the most‐common and convenient routes for delivering ...
Abstract The pulmonary route offers an exceptional, non-invasive administration site for drug delivery. The principal characteristics that make the lungs an appealing route for drug administration ...
occurs after 9–13 months of EGFR TKIs administration in nonsmall cell lung cancer (NSCLC). In this study, a pulmonary microspheres system that codelivers afatinib and paclitaxel (PTX) is developed ...
of the respiratory system. In this work, inspired by pollen in nature, novel shell–core aerosol particles (APs) capable of Brownian motion are constructed for respiratory delivery. Drugs ‐loaded poly(lactic‐co‐glycolic ...
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