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for studies of human tumour radiation biology and related physiological processes. MLS spheroids may be particularly useful in studies of therapeutic consequences of partial radiobiological hypoxia since ...
for studies of human tumour radiation biology and related physiological processes. MLS spheroids may be particularly useful in studies of therapeutic consequences of partial radiobiological hypoxia since ...
The interrelationship among external O2 and glucose supply, oxygenation status, oxygen consumption rates and cellular viability in tumour microregions was studied using the multicellular spheroid ...
The interrelationship among external O2 and glucose supply, oxygenation status, oxygen consumption rates and cellular viability in tumour microregions was studied using the multicellular spheroid ...
) cell cultures, including multicellular tumour spheroids and multicellular layers (MCLs), capture many features of real tumours , and have advantages over monolayer cell culture for developing drugs ...
in multicellular tumour spheroid and mouse models of prostate cancer. The cytotoxic effect of 212Pb-NG001 was tested in human prostate C4-2 spheroids . Biodistribution at various time points and therapeutic effects ...
: Human tumour cells, multicellular spheroids . metabolism, radiation , interferon. doxorubicin, gene therapy, oxygen sensing, angiogenesis, p02, pH, confocal microscopy, ...
We model the heterogeneous response to radiation of multicellular tumour spheroids assuming position- and volume-dependent radiosensitivity. We propose a method to calculate the overall ...
Abstract A critical step in the dissemination of ovarian cancer is the formation of multicellular spheroids from cells shed from the primary tumour . The objectives of this study were to apply ...
spheroid . These qualitative changes and extensions were necessary in order to allow for the study of realistic fractionation schemes as well as alternative radiation delivery timings. Tumour spheroids have ...
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