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Lipase-catalyzed synthesis of l -cysteine glucosyl esters in organic media

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Lipase-catalyzed synthesis of l -cysteine glucosyl esters in organic media

Abstract

New sugar amino acids were synthesized by enzymatic esterification of d -glucose with l -cysteine using immobilized lipase B from Candida antarctica in a mixed solvent system composed of 2-methyl-2-butanol and dimethyl sulfoxide. Addition of small quantities of water to the medium improved the glucose conversion yield by a factor of two.
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Title
Lipase-catalyzed synthesis of l -cysteine glucosyl esters in organic media
Author(s)
Valepyn, Emmanuel; Nys, Joel; Richel, Aurore; Laurent, Pascal; Berezina, Nathalie; Talon, Olivier; Paquot, Michel
Journal
Biocatalysis and Biotransformation , Volume 29 (1) Informa Healthcare – Jan 1, 2011
Publisher
Informa Health
Copyright
©© 2011 Informa UK, Ltd.
ISSN
1024-2422
eISSN
1029-2446
D.O.I.
10.3109/10242422.2010.548555
Publisher site
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