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irradiation also increases the number of colonic polyps, carcinomas and invasive adenocarcinomas. Pretreatment with the non-steroidal anti-inflammatory drug, CDDO-EA, reduces proton irradiation associated SIR ...
increased susceptibility to A. fumigatus infection. Due to pyroptosis in lung epithelial cells, it resulted in the destruction of the lung epithelial barrier and further damage to lung tissue . Moreover, we ...
studies using the LA-1 mouse model 70 days post-fractionated 1.0 Gy 1 GeV/n 56Fe IR, there was an increased expression of inflammatory factors within the lung (200 days prior to the observation of invasive ...
image Fig 4. Increased activation of β-catenin and NF-κB in heavy-ion exposed mouse colon. A) Representative images (200X) of active β-catenin-stained tumor-free ( normal ) and tumors from control, γ-rays ...
an increase in oxidative stress and the inflammatory response. Therefore, it is imperative to develop effective clinical radiological protection strategies for the radiological protection of the normal organs ...
C57L/J mouse to increase the reproducibility of positioning so that the entire thorax could be irradiated while sparing the surrounding organs. The pole faces of the electromagnet were 5 cm in diameter ...
orthotopically implanted mock- irradiated or irradiated mice with a limiting number of syngeneic glioma cells. Pre- irradiation of mouse brains resulted in a striking increase in tumor growth and invasion driven ...
-agent chemotherapy. The identification and validation of novel target molecules, which doesn’t disturb the normal postnatal physiology and development of the central nervous system and other tissues ...
) in an epidermoid carcinoma mouse xenograft. SWE was used for real-time mapping of the tumor stiffness, both during the two near infrared irradiation sessions and over the days after the treatment. We observed ...
-leaky tumors (e.g. GBM8) are similar as in normal brain. Although the drug levels are higher in leakier tumors (several models, including metastatic models), the levels further increase when the same ...
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