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Factors involved in reduced glutathione (GSH) and vitamin E‐mediated inhibition of NADPH‐dependent rat liver microsomal lipid peroxidation were examined. Lipid peroxidation was monitored over a time ...
Factors involved in reduced glutathione (GSH) and vitamin E‐mediated inhibition of NADPH‐dependent rat liver microsomal lipid peroxidation were examined. Lipid peroxidation was monitored over a time ...
Tocopherol -enriched liver microsomes are more resistant to lipid peroxidation at an alkaline pH of 8.5 in comparison with microsomes incubated at pH 7.5. An alkaline pH provides conditions for two ...
. Sesamol containing a free phenolic group inhibited lipid peroxidation in both the systems whereas sesamin and sesamolin having methylenedioxy groups were effective only in the microsomal system. Since ...
pretreated with α‐ tocopherol to inhibit lipid peroxidation or with vehicle (soybean oil) and then subjected to 60 min no‐flow hepatic ischemia in vivo. Control animals were time‐matched sham‐ischemic animals ...
Adriamycin or epirubicin, which were equally efficient. In each case peroxidation was iron-dependent and could be catalysed by ferritin. The antioxidants β-carotene and α- tocopherol inhibited lipid ...
was inhibited in similar manner by cytochrome P450 inhibitors. The results obtained led us to the following conclusions: (1) microsomal lipid peroxidation next to mitochondrial lipid peroxidation may ...
In this study, we examined the relative efficacies of α- tocopherol , N-acetyl-serotonin, and melatonin in reducing ascorbate-Fe2+ lipid peroxidation (LPO) of rat testicular microsomes and mitochondria ...
was well correlated to the TBA-RS formation, indicating that the chemiluminescence production was closely associated with the lipid peroxidation . 3 The addition of SKF-525A to the microsomal suspension ...
‐ tocopherol . NADPH‐ and ADP‐Fe3+‐dependent microsomal lipid peroxidation was efficiently inhibited by α‐ tocopherol , but not by uric acid. Uric acid seems to scavenge free radicals in hydrophilic conditions ...
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