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by Theralase Inc.. For in vitro studies, TLD1433 was diluted to 2 mM in autoclaved water and further diluted in media as required. In vivo formulation with human apo- transferrin (Sigma-Aldrich) was prepared ...
this hypothesis in vitro and in vivo . Materials and methods Reagents Erastin was purchased from AdooQ Bioscience (Irvine, CA) and ferrostatin-1 from Sigma-Aldrich (St. Louis, MO). The following antibodies were used ...
with 18F-FDG MRI, PET Theragnostic Preclinical (in vivo ) 28 Transferrin overexpression HK97-based viral nanoparticle conjugated with fluorescein-5-maleimide Optical Theragnostic Preclinical (in vitro ) 33 ...
lines in vitro and improve transferrin accumulation at breast metastatic sites in vivo . Our results confirm the frequent overexpression of transferrin receptor in all clinical and pathological classes ...
is the measured transferrin (including saturated and unsaturated). Preparation and quantification of carbonylated fibrinogen standard Fibrinogen (Sigma, St Louis, MO, USA) was oxidized in vitro by iron/ascorbate ...
to assays for bactericidal and opsonophagocytic activity in human sera in vitro [11,12]. To evaluate the protective efficacy of OMV vaccines against infection with serogroup B meningococci, we have previously ...
) Immunoliposomes with different acid sensitivities as probes for the cellular endocytic pathway . Biochim. Biophys. Acta. 987 : 47 – 55 . Google Scholar Crossref Search ADS PubMed WorldCat Collins , D. , Litzinger ...
or transferrin were demonstrated to occur under near-extracellular conditions, viz., in the presence of the major blood reducing agent, ascorbic acid .16 We note that this is not surprising as the adduct formation ...
that has 2 N-glycosylation sites, and each glycan contains ≤2 terminal, negatively charged sialic acids . The glycoforms of transferrin are widely used as a biomarker of N-glycosylation defects. Alterations ...
for instance peptides, nucleic acids , aptamers.[28,29] Among the classical targets, we can cite the transferrin receptors (TfR) or nicotinic acetylcholine receptors that allow the reach the environment of brain ...
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