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variation was distinctly different in adjacent retinas, retinomas and retinoblastomas . All (4/4) retinomas contained a proportion of cells displaying gains in some genes, indicating genomic instability (Fig ...
. Open in new tabDownload slide Open in new tabDownload slide human embryonic stem cells, human induced pluripotent stem cells, retinoblastoma , retinoma , single-cell RNA-Seq, retinal organoids Introduction ...
Introduction Retinoblastoma (Rb) is the most common pediatric intraocular neoplasm and occurs in 1 of every 15,000 births. It results from the biallelic inactivation of the RB1 tumor suppressor gene ...
of the US Center for Disease Control and Prevention (http://www.cdc.gov/ genomics /activities/famhx.htm) recognizes and promotes this need (9). Learning the clinical features that suggest the possibility ...
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