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genetic changes , including activation of dominantly acting oncogenes that promote cell proliferation and loss of tumor suppressor genes that negatively regulate cell proliferation.High-grade prostatic ...
Epigenetic mechanisms permit the stable inheritance of cellular properties without changes in DNA sequence or amount. In prostate carcinoma , epigenetic mechanisms are essential for development ...
Speaker abstracts neoplasia in prostate and invasive squamous cell carcinoma of the forestomach with high penetrance by 6 weeks of age. Both epithelial S.01 lesions were associated with an increased ...
Purpose of reviewTo highlight the latest changes in prostate cancer (PCa), urothelial carcinoma , upper tract urothelial carcinoma (UTUC) and renal cell carcinoma (RCC) diagnosis and the impact ...
Because a change from hormone‐sensitive to hormone‐resistant carcinoma of the prostate often occurs concomitantiy with genetic changes or as a result of the latter, the markers specific for prostatic ...
the androgen‐dependent prostate carcinoma cell line LNCaP and the androgen‐independent prostate carcinoma cell lines PC‐3 and DU 145. These clones were divided into four groups: androgen‐responsive genes (TL5 ...
modulates the further pathogenesis of prostate carcinoma . Summarising these epidemiological, genetic and cell biological aspects, infectious prostatitis might have a causative role in the complex ...
Recent studies have shown that intraductal prostate carcinoma (IDC‐P) should be considered as a separate lesion distinct from prostatic intraepithelial neoplasia (PIN). The purpose of the present ...
during several subcultivations of these cell lines, indicating genetic stability of these prostatic carcinoma cells in vitro. Thus individual cell lines derived from radical prostatectomy seem to represent ...
. In prostatic cancer, AKT1 was amplified in one carcinoma (2.6%). No genetic changes were observed for AKT2 and AKT3. High frequencies of aneusomy for all chromosomes were observed in breast and prostatic ...
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