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steroidogenic enzymes (11) are located in the endoplasmic reticulum (ER), often tightly bound to the membrane . The adrenal microsomal steroidogenic P450 enzymes are cytochrome (CY)P17, CYP19 (aromatase ...
of cytochrome P450s belonging to the CYP710A family as the plant C-22 desaturase. Recombinant proteins of CYP710A1 and CYP710A2 from Arabidopsis thaliana and CYP710A11 from tomato (Lycopersicon esculentum) were ...
oxidation and reduction reactions are primarily catalyzed by cytochrome P450 enzymes, a supergene family of heme-containing, mixed-function oxidase enzymes found in greatest concentration in the smooth ...
of reduction of cytochrome P450 -substrate complex, which in turn is dependent on the activation and turnover rates of NADPH- cytochrome c reductase, cytochrome b5 and on the total cytochrome P450 content [67 ...
, stomach, epididymis, or testis. Hepatic microsomal cytochrome P450 experiments revealed that single, high oral doses of DCE did not alter total P450 levels, but did induce CYP2E1 levels and activity ...
to be a deciding factor for the regulation of several hepatic features such as cytochromes P450 and glutathione S-tranferases (18, 29, 30), as well as for microsomal fatty acid composition (15). Link between LPL ...
lyase Amino acid transport and metabolism; coenzyme transport and metabolism gi|19572743 Cytochrome P-450 14DM 11.6 1.178 1.873 Cytochrome P450 Cytochrome P450 , family 51 (sterol 14-demethylase) gi ...
observed.31 In contrast, studies with DPH have reported a reduction in the membrane fluidity in erythrocyte and vascular smooth muscle cells,22 hepatocytes, synaptosomes, and cardiomyocytes32 from SHR ...
C18:3 in both leaves and roots, which maintained the membrane fluidity , and enhanced plant tolerance to cold, drought, and salt stresses. Notably, the constitutively increased C18:3 induced a sustained ...
genotoxins using yeast cell wall mutants and those expressing human cytochrome P450 genes. Introduction The authors have previously reported the construction and assessment of a yeast-based genotoxicity assay ...
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