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by angiotensin II (30pmol) by the venous circulation. Endothelin‐1 (30pmol) constricted both portions of the vasculature but the prolonged nature of its response was associated with only the venous vessels. 3 ...
We showed earlier that NO inhibition caused a left‐shift and augmented Emax of the concentration‐response curve of AT1‐mediated ( angiotensin II )‐induced vasoconstrictions (AII‐VC) in the rat kidney ...
. These results demonstrate that AII induces endothelium - dependent dilations at low concentrations, which reverses to a smooth muscle, AT1- dependent constriction at higher concentrations. Furthermore, the AII ...
Renal vasoconstriction in response to angiotensin II (ANGII) is known to be modulated by nitric oxide (NO). Since shear stress stimulates the release of a variety of vasoactive compounds from ...
Background: Impaired endothelium ‐ dependent and independent vasodilator responses in chronic heart failure (CHF) have been well described. Previous studies involved younger patients and omitted ...
of NO synthesis causes prominent constriction of renal arterioles [4, 5], and enhances the vasoconstrictor response to angiotensin II [4]and endothelium [6]. Although these observations clearly indicate ...
and endothelium ‐denuded aortic rings. LY294002 and wortmannin did not cause any potentiating effect on phenylephrine‐ and angiotensin II ‐induced concentration‐ dependent contractile responses in endothelium ‐intact ...
September 1999; accepted by M. J. Parnham 6 April 2000 Abstract. Objective: To demonstrate tissue selective brady- vasopressor octapeptide angiotensin II . ACE is also known as kinin (BK) potentiating action ...
( endothelium - dependent ) vasodilation was significantly improved in the small arteries of the losartan-treated subjects compared with baseline values, but not in subjects who were given atenolol. Angiotensin II ...
have the advantage of allowing us to observe the arteriolar diameter directly in the absence of systemic hemodynamic and hormonal influences. Using these preparations, we have found that angiotensin II ...
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