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(Gos) + TAM NS 41 3.2 0 32 Abbreviations: Bus, buserelin; CR, complete response ; CT, chemotherapy; EORTC, European Organization for Research and Treatment of Cancer; ET, endocrine therapy; Gos, goserelin ...
3 month injection and found persisting castrate levels of testosterone in 10 of the 13 patients at 6 months and hypogonadal symptoms persisting for a median of 13.6 months. Although an overwhelming ...
-negative (11) GROCTA 02 Lymph node-positive, receptor-positive 235 CMF × 6 Ovarian ablation + tamoxifen × 5 y No difference (12) ABCSG 5 Stage I/II, receptor-positive 1045 CMF × 6 Goserelin × 3 y ...
irradiation; Z = goserelin . Open in new tab Table 3 Randomized trials of adjuvant chemotherapy versus OA/OS Study . Patients . n . Treatment . Outcome . Jonat et al. (2002) [23] N+ 1,640 CMF × 6 versus Z × 2 ...
of fulvestrant are approximately twofold higher with repeated administration than those achieved following a single dose, and that it can take 3 – 6 months for fulvestrant to reach steady-state levels at the 250 mg ...
experienced disease recurrence or progression after previous endocrine therapy [ 6 ]. The FIRST and FALCON trials further demonstrated the superior efficacy of fulvestrant 500 mg compared with anastrozole ...
Context: GnRH agonist (GnRHa) monthly injections are frequently used in the treatment of central precocious puberty (CPP). The 3 -month leuprolide depot 11.25- and 30- mg formulations are newly ...
25–100 mg /day Leuprolide (GnRH agonist) Parenteral 3.75–7.5 mg IM depot monthly or 11.25 mg IM depot every 3 months 7.5 mg IM every month (goal testosterone ...
stage and metastatic BC HR+; post-menopausal Oral 1 mg od 50 h 1– 6 h (range) NR None Exemestane Early stage and metastatic BC HR+; post-menopausal Oral 25 mg od 24 h 1– 3 h NR None Letrozole Early stage ...
arm, but no difference in overall survival between the two arms. Table 6 Mitoxantrone plus glucocorticoid Randomized phase III comparison of mitoxantrane (12 mg /m2 every 3 weeks) plus prednisone (5 mg ...
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