Eli k. Marshall, jr. (1889-1966): from biochemistry and physiology to pharmacology and pharmacokinetics
Abstract
DRUG METABOLISM REVIEWS, 28(3), 31 1-344 (1996) ELI K. MARSHALL, JR. (1889-1966): FROM BIOCHEMISTRY AND PHYSIOLOGY TO PHARMACOLOGY AND PHARMACOKINETICS" MARCEL H. BICKEL Department o the History o Medicine f f University of Bern Buehlstrasse 26, CH-3012 Bern, Switzerland I. INTRODUCTION ........................................................ 11. BIOGRAPHICAL NOTE ................................................ 312 314 111. SCIENTIFIC WORK A. Biochemistry .. ... . .... ....., .................... .... ....... .......... B . Physiology .. .... .... .... ....... . ..... ......... ..... ............ ....... C. Pharmacology ......... . .... , ..... ..... . .... ......... ....... . ......... D. Miscellaneous Writings.. ... ........... ... . .... ...... ....... ....... .................................................... 316 316 3 16 3 18 326 335 336 IV. ASSESSMENT OF MARSHALL'S SCIENTIFIC WORK ...... 329 V. CONCLUSION ........................................................... Acknowledgment ............ .............................................. Notes and References.. .. ..... ..... . ......... . .... .................... . .. 337 *This manuscript was refereed by Frederick J. Di Carlo, Ph.D., U.S. Environmental Protection Agency, Washington, DC 20460. 311 Copyright Q 1996 by Marcel Dekker, Inc. 312 BICKEL I. INTRODUCTION Eli Kennerly Marshall, Jr. (1889-1966) was a pioneer in biomedical sciences in the first half of the 20th century. As a young scientist he made some remarkable contributions to the