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Effects of Physical Exercise on Sex Hormone Binding Globulin, High Density Lipoprotein Cholesterol, Total Cholesterol and Triglycerides in Postmenopausal Women

Endocrine Research , Volume 18 (4) – Jan 1, 1992

Details

Publisher
Informa UK Ltd
Copyright
© 1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted
Subject
Original Article
ISSN
0743-5800
eISSN
1532-4206
D.O.I.
10.3109/07435809209111036
Publisher site
See Article on Publisher Site

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Effects of Physical Exercise on Sex Hormone Binding Globulin, High Density Lipoprotein Cholesterol, Total Cholesterol and Triglycerides in Postmenopausal Women

Abstract

This study was performed on 18 postmenopausal female volunters in order to examine changes in sex hormone binding globulin (SHBG), high density lipoprotein cholesterol (HDLC), total cholesterol (TC) and serum triglyceride (TG) levels in a period of four months of moderate physical exercise. While SHBG decreased significantly (from 5 5. 3 ± 20.9 to 48.3 ± 21.0 nM, P < 0.051, TG increased significantly (from 87 ± 41.7 to 120.5 ± 57.5 mg/dl, P < 0.001). These changes were accompanied by a significant decrease (P < 0.001) in body fat content. Other parameters such as HDL- cholesterol, TC and BMI did not change significantly. Plasma levels of SHBG were negatively correlated to serum TG both at the beginning (r = 0.492, P < 0.05) and at the end (r = 0.538, P < 0.05) of the period of moderate exercise. Also, changes in SHBG were negatively correlated with changes in BMI (r = 0.585, P < 0. 0 5) and this could indicate that SHBG levels are more related to nutritional status than androgen/estrogen imbalance.
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